SOX8 and OLIG2

Number of citations of the paper that reports this interaction (PubMedID 16582099)
57

Data Source:
HPRD (in vitro)

		SOX8	OLIG2
Description		SRY-box transcription factor 8	oligodendrocyte transcription factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm Nuclear Transcription Factor Complex	Nuclear Chromatin Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Transcription Factor Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Identical Protein Binding Protein Dimerization Activity HMG Box Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation In Utero Embryonic Development Neural Crest Cell Migration Morphogenesis Of An Epithelium Signal Transduction Spermatogenesis Peripheral Nervous System Development Male Gonad Development Regulation Of Hormone Levels Positive Regulation Of Gliogenesis Neural Crest Cell Development Positive Regulation Of Osteoblast Proliferation Skeletal Muscle Cell Differentiation Negative Regulation Of Apoptotic Process Cell Fate Commitment Fat Cell Differentiation Negative Regulation Of Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Photoreceptor Cell Differentiation Cell Maturation Enteric Nervous System Development Oligodendrocyte Differentiation Sertoli Cell Development Astrocyte Fate Commitment Retina Development In Camera-type Eye Retinal Rod Cell Differentiation Adipose Tissue Development Morphogenesis Of A Branching Epithelium Renal Vesicle Induction Ureter Morphogenesis Metanephric Nephron Tubule Formation Positive Regulation Of Kidney Development Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis	Negative Regulation Of Transcription By RNA Polymerase II Spinal Cord Motor Neuron Differentiation Spinal Cord Oligodendrocyte Cell Fate Specification Thalamus Development Myelination Negative Regulation Of Neuron Differentiation Neuron Fate Commitment Positive Regulation Of Oligodendrocyte Differentiation
Pathways
Drugs
Diseases
GWAS		Logical memory (immediate recall) in normal cognition ( 29274321) Multiple sclerosis ( 31604244 21833088) Polycystic ovary syndrome ( 25574032)	Bulimia nervosa ( 23568457) Gastroesophageal reflux disease ( 31527586) Tea consumption ( 31046077)
Interacting Genes		18 interacting genes: CEBPA DLX5 EGR2 HHEX HOXC11 JAM2 JUN MMP1 NOD1 NR5A1 OLIG2 PAX3 PIDD1 POU3F3 POU5F1 SP1 TCF12 UTF1	5 interacting genes: CUL3 EP300 NKX2-2 SOX10 SOX8
Entrez ID		30812	10215
HPRD ID		16175	07334
Ensembl ID		ENSG00000005513	ENSG00000205927
Uniprot IDs		P57073	Q13516
PDB IDs
Enriched GO Terms of Interacting Partners?
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