EPN1 and PLEKHB2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		EPN1	PLEKHB2
Description		epsin 1	pleckstrin homology domain containing B2
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GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Clathrin-coated Pit	Integral Component Of Membrane Recycling Endosome Membrane
	Molecular Function	Protein Binding Lipid Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	In Utero Embryonic Development Endocytosis Notch Signaling Pathway Female Pregnancy Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Embryonic Organ Development Membrane Organization Negative Regulation Of Sprouting Angiogenesis	Regulation Of Cell Differentiation
Pathways		EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs		1,4-Diethylene Dioxide 1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS		Major depressive disorder ( 23377640)
Interacting Genes		24 interacting genes: AP2A1 AP2A2 CDK1 CEP126 CLTC CRMP1 DAZAP2 EPS15 EPS15L1 FBXO25 HIP1R LAPTM5 MAP3K1 MED31 PLEKHB2 REPS2 RNF11 SCNN1A SCNN1B SCNN1G SMURF1 TFAP2A UBC ZBTB16	9 interacting genes: ATF7IP BHLHE40 C1orf94 CDA DAZAP2 EPN1 MAP3K1 STAM2 UPF1
Entrez ID		29924	55041
HPRD ID		06270	15144
Ensembl ID		ENSG00000063245	ENSG00000115762
Uniprot IDs		A0A024R4S1 Q9Y6I3	A0A024QZ35 A0A0A0MSE9 A0A0A0MSI4 B4DJB7 Q96CS7
PDB IDs		1INZ 1KYD	3AJ4 3VIA
Enriched GO Terms of Interacting Partners?
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