PLEKHB2 and CDA

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PLEKHB2	CDA
Description		pleckstrin homology domain containing B2	cytidine deaminase
Image
GO Annotations	Cellular Component	Integral Component Of Membrane Recycling Endosome Membrane	Extracellular Region Cytosol Secretory Granule Lumen Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding	Nucleoside Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Regulation Of Cell Differentiation	Cell Surface Receptor Signaling Pathway Pyrimidine-containing Compound Salvage Cytidine Deamination Cytosine Metabolic Process Negative Regulation Of Cell Growth Pyrimidine Nucleoside Salvage Neutrophil Degranulation Negative Regulation Of Nucleotide Metabolic Process
Pathways			Neutrophil degranulation Pyrimidine salvage
Drugs			1-Beta-Ribofuranosyl-1,3-Diazepinone
Diseases
GWAS			Mean corpuscular volume ( 27863252) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		9 interacting genes: ATF7IP BHLHE40 C1orf94 CDA DAZAP2 EPN1 MAP3K1 STAM2 UPF1	10 interacting genes: FNDC11 KPNA2 LNX1 NTAQ1 PLEKHB2 PSMA1 PTGER3 SDCBP ZBTB24 ZNF598
Entrez ID		55041	978
HPRD ID		15144	11744
Ensembl ID		ENSG00000115762	ENSG00000158825
Uniprot IDs		A0A024QZ35 A0A0A0MSE9 A0A0A0MSI4 B4DJB7 Q96CS7	P32320
PDB IDs		3AJ4 3VIA	1MQ0
Enriched GO Terms of Interacting Partners?
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