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EPN1

Description epsin 1
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytosol
  • Plasma Membrane
  • Clathrin-coated Pit
Molecular Function
  • Protein Binding
  • Lipid Binding
Biological Process
  • In Utero Embryonic Development
  • Endocytosis
  • Notch Signaling Pathway
  • Female Pregnancy
  • Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
  • Embryonic Organ Development
  • Membrane Organization
  • Negative Regulation Of Sprouting Angiogenesis
Pathways
  • EGFR downregulation
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
Drugs
  • 1,4-Diethylene Dioxide
  • 1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS
  • Major depressive disorder ( 23377640)
Interacting Genes 24 interacting genes: AP2A1 AP2A2 CDK1 CEP126 CLTC CRMP1 DAZAP2 EPS15 EPS15L1 FBXO25 HIP1R LAPTM5 MAP3K1 MED31 PLEKHB2 REPS2 RNF11 SCNN1A SCNN1B SCNN1G SMURF1 TFAP2A UBC ZBTB16
Entrez ID 29924
HPRD ID 06270
Ensembl ID ENSG00000063245
Uniprot IDs A0A024R4S1 Q9Y6I3
PDB IDs 1INZ 1KYD
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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