TRIM42 and ARRDC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM42	ARRDC3
Description		tripartite motif containing 42	arrestin domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component		Lysosome Endosome Early Endosome Plasma Membrane
	Molecular Function	Protein Binding Zinc Ion Binding	Protein Binding Beta-3 Adrenergic Receptor Binding
	Biological Process		Temperature Homeostasis Negative Regulation Of Heat Generation Skin Development Positive Regulation Of Ubiquitin-protein Transferase Activity Fat Pad Development Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Negative Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Cold-induced Thermogenesis
Pathways
Drugs
Diseases
GWAS		Bipolar disorder (body mass index interaction) ( 24322204) Refractive astigmatism ( 25367360)	Breast cancer ( 29059683 25038754) Breast cancer (prognosis) ( 23319801) Breast cancer (survival) ( 25526632) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		64 interacting genes: ADAMTSL4 ARMC7 ARNT2 ARRDC3 AXIN1 BEX2 C1orf109 CARD9 CBY2 CCDC33 CDCA7L CEP70 EFHC2 EMD GLI1 GLRX3 GLYCTK GOLGA2 HOXA1 IHO1 IKZF3 IQUB KCTD9 KLHL38 KRT13 KRT15 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-2 L3MBTL2 LONRF1 LZTS2 MAGOHB MEOX2 MFAP1 MID2 MTUS2 MVP NOTCH2NLA PLSCR1 PNMA1 PSMA1 PSMD9 PTGER3 RAMAC RCOR3 RUNX1T1 SCNM1 SSX2IP STK16 TASOR2 TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VPS37A YWHAQ ZBTB1	14 interacting genes: ADRB2 BAG3 DCUN1D1 F2R HPGDS ITCH MAGI2 MORF4L1 OTUB2 PDCD6IP STAM2 TNFAIP3 TRIM42 UBE2E2
Entrez ID		287015	57561
HPRD ID		15559	09810
Ensembl ID		ENSG00000155890	ENSG00000113369
Uniprot IDs		Q8IWZ5	Q96B67
PDB IDs			4N7H 4R7V 4R7X
Enriched GO Terms of Interacting Partners?
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