TRIM42 and VPS37A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM42	VPS37A
Description		tripartite motif containing 42	VPS37A subunit of ESCRT-I
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		ESCRT I Complex Nucleoplasm Centrosome Cytosol Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Host Cell
	Molecular Function	Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process		Protein Targeting To Membrane Protein Targeting To Vacuole Endosomal Transport Macroautophagy Viral Life Cycle Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Transport Of Virus
Pathways			Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Bipolar disorder (body mass index interaction) ( 24322204) Refractive astigmatism ( 25367360)	Metabolite levels ( 23823483) Schizophrenia ( 28991256) Tonometry ( 17903302)
Interacting Genes		64 interacting genes: ADAMTSL4 ARMC7 ARNT2 ARRDC3 AXIN1 BEX2 C1orf109 CARD9 CBY2 CCDC33 CDCA7L CEP70 EFHC2 EMD GLI1 GLRX3 GLYCTK GOLGA2 HOXA1 IHO1 IKZF3 IQUB KCTD9 KLHL38 KRT13 KRT15 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-2 L3MBTL2 LONRF1 LZTS2 MAGOHB MEOX2 MFAP1 MID2 MTUS2 MVP NOTCH2NLA PLSCR1 PNMA1 PSMA1 PSMD9 PTGER3 RAMAC RCOR3 RUNX1T1 SCNM1 SSX2IP STK16 TASOR2 TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VPS37A YWHAQ ZBTB1	7 interacting genes: APP HGS KDM1A TRIM42 TSG101 UBC VPS28
Entrez ID		287015	137492
HPRD ID		15559	13410
Ensembl ID		ENSG00000155890	ENSG00000155975
Uniprot IDs		Q8IWZ5	Q8NEZ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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