NEK8 and NEK9

Number of citations of the paper that reports this interaction (PubMedID 11864968)
22

Data Source:
BioGRID (enzymatic study)

		NEK8	NEK9
Description		NIMA related kinase 8	NIMA related kinase 9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cilium Ciliary Inversin Compartment Ciliary Base	Nucleus Centrosome Cytosol
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Chromosome Segregation Determination Of Left/right Symmetry Heart Development Animal Organ Morphogenesis Regulation Of Hippo Signaling	Protein Phosphorylation Mitotic Nuclear Envelope Disassembly Cell Division
Pathways			Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
Drugs
Diseases		Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS		Reticulocyte count ( 27863252)	Coronary artery disease ( 29212778) Feeling fed-up ( 29500382)
Interacting Genes		6 interacting genes: ACVR1 NEK9 TCF4 TGFBR1 TRIM69 UBC	18 interacting genes: BICD2 CSN2 GZMB IFT43 JDP2 LIN52 MALL MBP MPP5 NEK6 NEK7 NEK8 RAN RARG RPS6KL1 SSRP1 SUPT16H WDR33
Entrez ID		284086	91754
HPRD ID		14822	11386
Ensembl ID		ENSG00000160602	ENSG00000119638
Uniprot IDs		Q86SG6	Q6PKF2 Q8TD19
PDB IDs			3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?
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