NEK9 and MPP5

		NEK9	MPP5
Description		NIMA related kinase 9	membrane palmitoylated protein 5
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GO Annotations	Cellular Component	Nucleus Centrosome Cytosol	Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Adherens Junction Bicellular Tight Junction Apical Plasma Membrane Axon Protein-containing Complex Myelin Sheath Adaxonal Region Perikaryon Lateral Loop Schmidt-Lanterman Incisure Extracellular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding	Protein Binding ATP Binding Protein Domain Specific Binding
	Biological Process	Protein Phosphorylation Mitotic Nuclear Envelope Disassembly Cell Division	Morphogenesis Of An Epithelial Sheet Peripheral Nervous System Myelin Maintenance Myelin Assembly Protein Localization To Myelin Sheath Abaxonal Region Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Establishment Of Epithelial Cell Polarity
Pathways		Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation	Tight junction interactions
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Feeling fed-up ( 29500382)
Interacting Genes		18 interacting genes: BICD2 CSN2 GZMB IFT43 JDP2 LIN52 MALL MBP MPP5 NEK6 NEK7 NEK8 RAN RARG RPS6KL1 SSRP1 SUPT16H WDR33	8 interacting genes: ARF6 CRB3 LIN7A MPP4 NEK9 PARD6B PATJ SOCS4
Entrez ID		91754	64398
HPRD ID		11386	09508
Ensembl ID		ENSG00000119638	ENSG00000072415
Uniprot IDs		Q6PKF2 Q8TD19	Q658X5 Q8N3R9
PDB IDs		3ZKE 3ZKF	1Y76 3UIT 4UU5 4UU6 4WSI
Enriched GO Terms of Interacting Partners?
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