HPGDS and ABHD17A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HPGDS	ABHD17A
Description		hematopoietic prostaglandin D synthase	abhydrolase domain containing 17A, depalmitoylase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle	Plasma Membrane Endosome Membrane Membrane Cell Junction Dendritic Spine Recycling Endosome Membrane Glutamatergic Synapse Anchored Component Of Postsynaptic Density Membrane Anchored Component Of Postsynaptic Recycling Endosome Membrane
	Molecular Function	Magnesium Ion Binding Glutathione Transferase Activity Prostaglandin-D Synthase Activity Calcium Ion Binding Protein Binding Protein Homodimerization Activity	Protein Binding Palmitoyl-(protein) Hydrolase Activity
	Biological Process	Prostaglandin Metabolic Process Glutathione Metabolic Process Signal Transduction Locomotory Behavior Cyclooxygenase Pathway Glutathione Derivative Biosynthetic Process Negative Regulation Of Male Germ Cell Proliferation	Protein Depalmitoylation Protein Palmitoylation Protein Localization To Membrane Regulation Of Postsynapse Organization Negative Regulation Of Protein Localization To Microtubule Positive Regulation Of Protein Localization To Endosome
Pathways		Glutathione conjugation Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs		Glutathione Vitamin A Tretinoin 2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride 3-phenyl-5-(1H-pyrazol-3-yl)isoxazole PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE Tranilast 4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid 4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE nocodazole 3-(4-nitrophenyl)-1H-pyrazole 1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID Glycerin
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Blood protein levels ( 30072576 29875488) Testicular germ cell tumor ( 28604728 28604732 23666239)
Interacting Genes		4 interacting genes: ABHD17A ARRDC3 HK3 MELTF	13 interacting genes: BIRC2 EHMT2 GOLGA2 GPC4 HPGDS KRTAP5-9 MDFI PLSCR4 PNMA1 RGS20 TNIP1 TRAF1 TRIM27
Entrez ID		27306	81926
HPRD ID		04001	07475
Ensembl ID		ENSG00000163106	ENSG00000129968
Uniprot IDs		A0A384P5J0 O60760	Q96GS6
PDB IDs		1IYH 1IYI 1V40 2CVD 2VCQ 2VCW 2VCX 2VCZ 2VD0 2VD1 3EE2 3KXO 3VI5 3VI7 4EC0 4EDY 4EDZ 4EE0 5AIS 5AIV 5AIX 5YWE 5YWX 5YX1 6N4E
Enriched GO Terms of Interacting Partners?
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