GLA and PLP1

		GLA	PLP1
Description		galactosidase alpha	proteolipid protein 1
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Lysosome Golgi Apparatus Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome	Plasma Membrane Integral Component Of Membrane Myelin Sheath Synapse
	Molecular Function	Catalytic Activity Alpha-galactosidase Activity Signaling Receptor Binding Protein Binding Hydrolase Activity Galactoside Binding Protein Homodimerization Activity Raffinose Alpha-galactosidase Activity	Structural Molecule Activity Protein Binding Structural Constituent Of Myelin Sheath
	Biological Process	Glycosphingolipid Metabolic Process Oligosaccharide Metabolic Process Glycoside Catabolic Process Neutrophil Degranulation Negative Regulation Of Nitric Oxide Biosynthetic Process Glycosylceramide Catabolic Process Glycosphingolipid Catabolic Process Negative Regulation Of Nitric-oxide Synthase Activity	Inflammatory Response Integrin-mediated Signaling Pathway Chemical Synaptic Transmission Axon Ensheathment Glial Cell Differentiation Positive Regulation Of Gene Expression Astrocyte Development Substantia Nigra Development Central Nervous System Myelination Neuron Projection Development Myelination Long-chain Fatty Acid Biosynthetic Process Axon Development
Pathways		Glycosphingolipid metabolism Neutrophil degranulation
Drugs		Migalastat
Diseases		Fabry disease	Hereditary spastic paraplegia (SPG) Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS
Interacting Genes		13 interacting genes: ANKRD30A CCR2 COL4A5 DUSP6 GPR17 GUCY2F HNRNPH2 MORF4L2 NAP1L3 NOSTRIN PDE6B PLP1 TERT	13 interacting genes: AKT1 BCL2L13 CALR CANX CLN8 CREB3 CREB3L1 GLA ITGAV LMNA MAG MBP PTPRN
Entrez ID		2717	5354
HPRD ID		02357	02321
Ensembl ID		ENSG00000102393	ENSG00000123560
Uniprot IDs		P06280 Q53Y83	A0A0S2Z4D4 A8K9L3 B4DI30 P60201
PDB IDs		1R46 1R47 3GXN 3GXP 3GXT 3HG2 3HG3 3HG4 3HG5 3LX9 3LXA 3LXB 3LXC 3S5Y 3S5Z 3TV8 4NXS 6IBK 6IBM 6IBR 6IBT	2XPG
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?