KLHL3 and GNAO1

Number of citations of the paper that reports this interaction (PubMedID 11259487)
11

Data Source:
HPRD (in vivo)

		KLHL3	GNAO1
Description		kelch like family member 3	G protein subunit alpha o1
Image
GO Annotations	Cellular Component	Cytosol Cytoskeleton Cul3-RING Ubiquitin Ligase Complex	Heterotrimeric G-protein Complex Plasma Membrane Dendrite Cell Body
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding	G Protein-coupled Receptor Binding GTPase Activity GTP Binding G-protein Beta/gamma-subunit Complex Binding G Protein-coupled Serotonin Receptor Binding Mu-type Opioid Receptor Binding Metal Ion Binding Corticotropin-releasing Hormone Receptor 1 Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Post-translational Protein Modification Ion Homeostasis Selective Autophagy Renal Sodium Ion Absorption Protein K48-linked Ubiquitination Distal Tubule Morphogenesis	Protein Folding Muscle Contraction Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Dopamine Receptor Signaling Pathway Wnt Signaling Pathway, Calcium Modulating Pathway Locomotory Behavior Regulation Of Heart Contraction
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	PLC beta mediated events PLC beta mediated events G-protein activation Ca2+ pathway Ca2+ pathway Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases
GWAS		Bronchopulmonary dysplasia ( 23897914) Heart failure ( 31919418) Severe malaria ( 29381699) Severe malaria (adjusted for sickle cell variant rs334) ( 29381699)	Chronotype ( 30696823) Diastolic blood pressure ( 30578418) Dimensional psychopathology (Positive) ( 29496196) Metabolite levels ( 23823483) Mitochondrial DNA copy number ( 30704525) Morning person ( 30696823) Pulse pressure ( 27841878) Sleep duration (short sleep) ( 30846698)
Interacting Genes		16 interacting genes: AKT1 CFAP206 CUL3 GNAI1 GNAO1 KEAP1 KLHL12 MORF4L2 OPRD1 PPP3CA PRKACA SYNCRIP SYT2 WNK1 WNK3 WNK4	34 interacting genes: ADORA1 ADRA2A ADRA2C CACNA1B CCR5 CRHR1 DCTN2 FFAR2 GABBR1 GNAI1 GPSM2 GRM6 HRH4 KLHL3 NGB NUCB1 OPRD1 OPRM1 PDE6G PDE6H PTPRU RGS1 RGS10 RGS14 RGS16 RGS19 RGS20 RGS4 RGS5 RGS7 RIC8A S1PR5 SCN8A TSHR
Entrez ID		26249	2775
HPRD ID		09011	00757
Ensembl ID		ENSG00000146021	ENSG00000087258
Uniprot IDs		Q9UH77	B3KP89 P09471 Q6AWC5 Q8N6I9
PDB IDs		4CH9 4HXI 5NKP	6FUF 6G79 6OIK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?