GNAO1 and GPSM2

Number of citations of the paper that reports this interaction (PubMedID 12925752)
20

Data Source:
HPRD (in vitro)

		GNAO1	GPSM2
Description		G protein subunit alpha o1	G protein signaling modulator 2
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GO Annotations	Cellular Component	Heterotrimeric G-protein Complex Plasma Membrane Dendrite Cell Body	Cell Cytoplasm Centrosome Cytosol Cell Cortex Lateral Plasma Membrane Protein-containing Complex Mitotic Spindle Pole Lateral Cell Cortex Cell Cortex Region
	Molecular Function	G Protein-coupled Receptor Binding GTPase Activity GTP Binding G-protein Beta/gamma-subunit Complex Binding G Protein-coupled Serotonin Receptor Binding Mu-type Opioid Receptor Binding Metal Ion Binding Corticotropin-releasing Hormone Receptor 1 Binding	Nucleotide Binding G-protein Alpha-subunit Binding GDP-dissociation Inhibitor Activity Protein Binding Protein C-terminus Binding Protein Domain Specific Binding Identical Protein Binding Protein Self-association Dynein Complex Binding
	Biological Process	Protein Folding Muscle Contraction Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Dopamine Receptor Signaling Pathway Wnt Signaling Pathway, Calcium Modulating Pathway Locomotory Behavior Regulation Of Heart Contraction	Establishment Of Mitotic Spindle Orientation Mitotic Spindle Organization G Protein-coupled Receptor Signaling Pathway Ran Protein Signal Transduction Regulation Of Catalytic Activity Cell Division Maintenance Of Centrosome Location Regulation Of Mitotic Spindle Organization Positive Regulation Of Protein Localization To Cell Cortex Positive Regulation Of Spindle Assembly
Pathways		PLC beta mediated events PLC beta mediated events G-protein activation Ca2+ pathway Ca2+ pathway Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	G alpha (i) signalling events
Drugs
Diseases
GWAS		Chronotype ( 30696823) Diastolic blood pressure ( 30578418) Dimensional psychopathology (Positive) ( 29496196) Metabolite levels ( 23823483) Mitochondrial DNA copy number ( 30704525) Morning person ( 30696823) Pulse pressure ( 27841878) Sleep duration (short sleep) ( 30846698)	Fat distribution (HIV) ( 21897333)
Interacting Genes		34 interacting genes: ADORA1 ADRA2A ADRA2C CACNA1B CCR5 CRHR1 DCTN2 FFAR2 GABBR1 GNAI1 GPSM2 GRM6 HRH4 KLHL3 NGB NUCB1 OPRD1 OPRM1 PDE6G PDE6H PTPRU RGS1 RGS10 RGS14 RGS16 RGS19 RGS20 RGS4 RGS5 RGS7 RIC8A S1PR5 SCN8A TSHR	10 interacting genes: AGR2 CLCC1 GLIS2 GNAI1 GNAI2 GNAI3 GNAO1 HRAS INSC NUMA1
Entrez ID		2775	29899
HPRD ID		00757	06609
Ensembl ID		ENSG00000087258	ENSG00000121957
Uniprot IDs		B3KP89 P09471 Q6AWC5 Q8N6I9	A0A024R0F8 B4DIF1 P81274
PDB IDs		6FUF 6G79 6OIK	3SF4 4WND 4WNE 4WNF 4WNG 5A6C 6HC2
Enriched GO Terms of Interacting Partners?
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