LTN1 and HES4

Number of citations of the paper that reports this interaction (PubMedID 20195357)
30

Data Source:
BioGRID (pull down)

		LTN1	HES4
Description		listerin E3 ubiquitin protein ligase 1	hes family bHLH transcription factor 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol RQC Complex	Nuclear Chromatin Nucleus
	Molecular Function	Protein Binding Zinc Ion Binding Ribosomal Large Subunit Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Transcription Factor Binding Protein Dimerization Activity E-box Binding N-box Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Cell Differentiation Negative Regulation Of Neuron Differentiation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 27863252) Hip circumference ( 28552196) Initial pursuit acceleration in psychotic disorders ( 29064472) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		8 interacting genes: HES4 IRF7 STING1 TIRAP UBC UBE2D1 UBE2D2 UBE2L3	5 interacting genes: COPG2 LTN1 PCBD1 PCBD2 RGS3
Entrez ID		26046	57801
HPRD ID		10327	16273
Ensembl ID		ENSG00000198862	ENSG00000188290
Uniprot IDs		O94822	D6REB3 E9PB28 Q9HCC6
PDB IDs		3J92
Enriched GO Terms of Interacting Partners?
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