SETBP1 and SET

Number of citations of the paper that reports this interaction (PubMedID 11231286)
26

Data Source:
HPRD (two hybrid, in vivo)

		SETBP1	SET
Description		SET binding protein 1	SET nuclear proto-oncogene
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Nuclear Body	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	DNA Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity Histone Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	DNA Replication Nucleosome Assembly Nucleosome Disassembly Viral Process Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Histone Acetylation Regulation Of MRNA Stability Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Transcription, DNA-templated
Pathways			Condensation of Prophase Chromosomes HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases		Schinzel-Giedion midface retraction syndrome
GWAS		Bone ultrasound measurement (velocity of sound) ( 28472463) Breast cancer ( 25751625 29059683 31757997) Coronary artery aneurysm in Kawasaki disease ( 27171184) Diastolic blood pressure ( 27618452) Estimated glomerular filtration rate ( 31152163) Hair color ( 26926045) Heel bone mineral density ( 30598549) Male-pattern baldness ( 29146897 22693459 28196072) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Number of sexual partners ( 30643258) Platelet thrombus formation ( 22550155) Pulse pressure ( 27841878) QRS duration ( 30679814 27577874 30012220 25035420 27659466) QRS interval (sulfonylurea treatment interaction) ( 27958378) Restless legs syndrome ( 29029846) Systolic blood pressure ( 27841878 28739976 27618452) Waist circumference ( 28552196)	Axial length ( 24144296) Body mass index ( 26426971) Eating disorders (purging via substances) ( 23568457)
Interacting Genes		12 interacting genes: APP DENND11 LRRC37A11P PLEKHF2 SET SPANXA1 SPANXC SPANXD SUMO1P1 UBE2I XAGE1B YAF2	54 interacting genes: ANP32A APEX1 APP CALM1 CDK5 CDK5R1 CDKN1A CHAF1A CHRM2 CHRM3 ELAVL1 ELF4 EP300 ESR1 FAM111B FBXO7 FOS FOXO1 GZMA GZMK H2BC1 H3-3A H3-4 H4-16 H4C14 HMGB2 IRF1 JUNB KLF5 KMT2A LGMN MDM2 MEOX2 MTERF1 NME1 NUCB1 NUPR1 PIK3CG PPP2CA PPP2R1B PRKAR1A PTMA RAC1 SDCBP SETBP1 SGO1 TAF1A TERF1 TERF2 TERF2IP THAP7 TREX1 UCHL5 XRCC6
Entrez ID		26040	6418
HPRD ID		10224	09023
Ensembl ID		ENSG00000152217	ENSG00000119335
Uniprot IDs		Q9Y6X0	A0A024R895 A0A0C4DFV9 Q01105 Q5VXV3
PDB IDs			2E50
Enriched GO Terms of Interacting Partners?
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