SETBP1 and DENND11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SETBP1	DENND11
Description		SET binding protein 1	DENN domain containing 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Nuclear Body
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Schinzel-Giedion midface retraction syndrome
GWAS		Bone ultrasound measurement (velocity of sound) ( 28472463) Breast cancer ( 25751625 29059683 31757997) Coronary artery aneurysm in Kawasaki disease ( 27171184) Diastolic blood pressure ( 27618452) Estimated glomerular filtration rate ( 31152163) Hair color ( 26926045) Heel bone mineral density ( 30598549) Male-pattern baldness ( 29146897 22693459 28196072) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Number of sexual partners ( 30643258) Platelet thrombus formation ( 22550155) Pulse pressure ( 27841878) QRS duration ( 30679814 27577874 30012220 25035420 27659466) QRS interval (sulfonylurea treatment interaction) ( 27958378) Restless legs syndrome ( 29029846) Systolic blood pressure ( 27841878 28739976 27618452) Waist circumference ( 28552196)
Interacting Genes		12 interacting genes: APP DENND11 LRRC37A11P PLEKHF2 SET SPANXA1 SPANXC SPANXD SUMO1P1 UBE2I XAGE1B YAF2	1 interacting genes: SETBP1
Entrez ID		26040	57189
HPRD ID		10224	13976
Ensembl ID		ENSG00000152217	ENSG00000257093
Uniprot IDs		Q9Y6X0	A4D1U4
PDB IDs
Enriched GO Terms of Interacting Partners?
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