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SET

Description SET nuclear proto-oncogene
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Endoplasmic Reticulum
  • Lipid Droplet
  • Cytosol
  • Protein-containing Complex
  • Perinuclear Region Of Cytoplasm
Molecular Function
  • DNA Binding
  • Protein Phosphatase Inhibitor Activity
  • Protein Binding
  • Protein Phosphatase Regulator Activity
  • Histone Binding
Biological Process
  • DNA Replication
  • Nucleosome Assembly
  • Nucleosome Disassembly
  • Viral Process
  • Negative Regulation Of Phosphoprotein Phosphatase Activity
  • Negative Regulation Of Histone Acetylation
  • Regulation Of MRNA Stability
  • Negative Regulation Of Neuron Apoptotic Process
  • Negative Regulation Of Transcription, DNA-templated
Pathways
  • Condensation of Prophase Chromosomes
  • HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases
GWAS
  • Axial length ( 24144296)
  • Body mass index ( 26426971)
  • Eating disorders (purging via substances) ( 23568457)
Interacting Genes 54 interacting genes: ANP32A APEX1 APP CALM1 CDK5 CDK5R1 CDKN1A CHAF1A CHRM2 CHRM3 ELAVL1 ELF4 EP300 ESR1 FAM111B FBXO7 FOS FOXO1 GZMA GZMK H2BC1 H3-3A H3-4 H4-16 H4C14 HMGB2 IRF1 JUNB KLF5 KMT2A LGMN MDM2 MEOX2 MTERF1 NME1 NUCB1 NUPR1 PIK3CG PPP2CA PPP2R1B PRKAR1A PTMA RAC1 SDCBP SETBP1 SGO1 TAF1A TERF1 TERF2 TERF2IP THAP7 TREX1 UCHL5 XRCC6
Entrez ID 6418
HPRD ID 09023
Ensembl ID ENSG00000119335
Uniprot IDs A0A024R895 A0A0C4DFV9 Q01105 Q5VXV3
PDB IDs 2E50
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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