RCHY1 and HOXA2

Number of citations of the paper that reports this interaction (PubMedID 24244684)
4

Data Source:
BioGRID (protein complementation assay, affinity chromatography technology)

		RCHY1	HOXA2
Description		ring finger and CHY zinc finger domain containing 1	homeobox A2
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Intracellular Membrane-bounded Organelle	Nuclear Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	P53 Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Error-free Translesion Synthesis	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Determination Osteoblast Development Segment Specification Motor Neuron Axon Guidance Anterior/posterior Pattern Specification Dorsal/ventral Pattern Formation Rhombomere 2 Development Rhombomere 3 Morphogenesis Brain Segmentation Middle Ear Morphogenesis Negative Regulation Of Neuron Differentiation Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Viscerocranium Morphogenesis Cellular Response To Retinoic Acid
Pathways		Translesion Synthesis by POLH Antigen processing: Ubiquitination & Proteasome degradation	Activation of anterior HOX genes in hindbrain development during early embryogenesis Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Response to tocilizumab in rheumatoid arthritis ( 22491018)	Chronic venous disease ( 28374850) Tonsillectomy ( 27182965 28928442)
Interacting Genes		69 interacting genes: ADAMTSL4 AIG1 ANGPTL8 AOX1 AR ARF4 ATN1 BIRC3 CAMK2A CAMK2G CDK9 CDKN1B CHD8 CHEK2 COPE COX6C CYBA DAPK1 DCUN1D5 F7 FADS6 GFI1B GORAB HOXA2 HOXB1 HOXB5 HOXC4 HRG KAT5 KLHL41 KRTAP9-2 LIMS2 MDM2 MEOX2 MSH3 MT2A NKD2 NLK NOTCH2NLA PGLS PLAGL2 PMM1 PRDX4 RAB11A RBM38 RILP RPLP1 RPN2 SEMA4C SERPINA1 SERPINA5 SERTAD1 SRPRB TAOK2 TMBIM1 TMEM14C TMEM184A TP53 TP63 TP73 TRIM8 UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 WDR74 ZNF160	5 interacting genes: DMPK MEIS1 NDE1 RALA RCHY1
Entrez ID		25898	3199
HPRD ID		07607	05252
Ensembl ID		ENSG00000163743	ENSG00000105996
Uniprot IDs		Q96PM5	O43364
PDB IDs		2JRJ 2K2C 2K2D
Enriched GO Terms of Interacting Partners?
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