RCHY1 and SERTAD1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RCHY1	SERTAD1
Description		ring finger and CHY zinc finger domain containing 1	SERTA domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm
	Molecular Function	P53 Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Error-free Translesion Synthesis	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Proliferation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Translesion Synthesis by POLH Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Response to tocilizumab in rheumatoid arthritis ( 22491018)	Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)
Interacting Genes		69 interacting genes: ADAMTSL4 AIG1 ANGPTL8 AOX1 AR ARF4 ATN1 BIRC3 CAMK2A CAMK2G CDK9 CDKN1B CHD8 CHEK2 COPE COX6C CYBA DAPK1 DCUN1D5 F7 FADS6 GFI1B GORAB HOXA2 HOXB1 HOXB5 HOXC4 HRG KAT5 KLHL41 KRTAP9-2 LIMS2 MDM2 MEOX2 MSH3 MT2A NKD2 NLK NOTCH2NLA PGLS PLAGL2 PMM1 PRDX4 RAB11A RBM38 RILP RPLP1 RPN2 SEMA4C SERPINA1 SERPINA5 SERTAD1 SRPRB TAOK2 TMBIM1 TMEM14C TMEM184A TP53 TP63 TP73 TRIM8 UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 WDR74 ZNF160	39 interacting genes: ADCY1 ASB8 ATXN7L3 CCND2 CDK4 CDKN2A CHURC1 CIB3 COPB1 CREBBP DENND4A EGLN3 ELOC EP300 FAH HIVEP1 HSPB1 KAT2B KLHL42 MVP NEDD4 P4HA3 PATE1 POT1 PRDM4 RBX1 RCHY1 ROPN1 SETD7 SFI1 SMAD3 SPEN STAT5B SUPT7L TGM2 TLR4 TRIM28 XIAP ZNF410
Entrez ID		25898	29950
HPRD ID		07607	15326
Ensembl ID		ENSG00000163743	ENSG00000197019
Uniprot IDs		Q96PM5	Q53GC0 Q9UHV2
PDB IDs		2JRJ 2K2C 2K2D
Enriched GO Terms of Interacting Partners?
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