USP49 and TRIM35

Number of citations of the paper that reports this interaction (PubMedID 23105109)
16

Data Source:
BioGRID (two hybrid)

		USP49	TRIM35
Description		ubiquitin specific peptidase 49	tripartite motif containing 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Nucleus Cytoplasm
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Histone Binding	Molecular_function Zinc Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Histone H2B Conserved C-terminal Lysine Deubiquitination	Apoptotic Process Positive Regulation Of Apoptotic Process Innate Immune Response Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Viral Release From Host Cell
Pathways		Ub-specific processing proteases	Interferon gamma signaling
Drugs
Diseases
GWAS		Cutaneous psoriasis ( 26626624) Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 23263863 20139978 27863252) Red blood cell count ( 20139978 27863252) Skin aging (microtopography measurement) ( 28502801) Sleep duration (short sleep) ( 30846698)	Chronotype ( 30696823) Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Lung cancer ( 28604730)
Interacting Genes		9 interacting genes: FKBP5 H2BC21 MED17 MED18 MED8 RBCK1 STING1 TP53 TRIM35	14 interacting genes: PAN2 PKM TRIM11 TRIM5 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2U UBE2W USP2 USP49
Entrez ID		25862	23087
HPRD ID		10075	15553
Ensembl ID		ENSG00000164663	ENSG00000104228
Uniprot IDs		Q70CQ1	E5RGB3 Q9UPQ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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