MLC1 and TPT1

Number of citations of the paper that reports this interaction (PubMedID 12149273)
43

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		MLC1	TPT1
Description		modulator of VRAC current 1	tumor protein, translationally-controlled 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Early Endosome Endoplasmic Reticulum Plasma Membrane Caveola Cell-cell Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Raft Perinuclear Region Of Cytoplasm Recycling Endosome Astrocyte End-foot	Spindle Pole Extracellular Space Cell Nucleus Cytoplasm Multivesicular Body Cytosol Cytoplasmic Microtubule Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding Protein-containing Complex Binding	RNA Binding Calcium Ion Binding Protein Binding
	Biological Process	Ion Transport Protein Transport Vesicle-mediated Transport Positive Regulation Of Intracellular Transport Regulation Of Response To Osmotic Stress Cellular Response To Cholesterol Caveolin-mediated Endocytosis	Calcium Ion Transport Cellular Calcium Ion Homeostasis Response To Virus Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways
Drugs			Calcium Citrate Calcium Phosphate
Diseases		Megalencephalic leukoencephalopathy with subcortical cysts (MLC)
GWAS		Acne (severe) ( 24927181) Body mass index (adult) ( 28430825)	Type 2 diabetes ( 25760438)
Interacting Genes		7 interacting genes: DAPK2 KDM1A MYLK NAT14 PRMT6 ROCK1 TPT1	30 interacting genes: APP ATP1A1 ATP1A2 BCL2L1 CALM1 DBN1 EEF1A1 EEF1A2 EEF1B2 EEF1D FANCA HSPB1 IKBKG LIG4 MCL1 MCPH1 MDM2 MLC1 NKX3-1 NOTCH3 PER2 PLK1 RBBP6 RPLP1 SNX6 SPP1 STEAP3 TRIP13 TUBB2A VHL
Entrez ID		23209	7178
HPRD ID		05800	15979
Ensembl ID		ENSG00000100427	ENSG00000133112
Uniprot IDs		A0A024R4V4 Q15049	A0A024RDY2 A0A0B4J2C3 A0A0P1J1R0 P13693
PDB IDs			1YZ1 2HR9 3EBM 4Z9V 5O9L 5O9M
Enriched GO Terms of Interacting Partners?
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