TPT1 and RPLP1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		TPT1	RPLP1
Description		tumor protein, translationally-controlled 1	ribosomal protein lateral stalk subunit P1
Image
GO Annotations	Cellular Component	Spindle Pole Extracellular Space Cell Nucleus Cytoplasm Multivesicular Body Cytosol Cytoplasmic Microtubule Extracellular Exosome	Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding	Structural Constituent Of Ribosome Protein Binding Protein Kinase Activator Activity Ribonucleoprotein Complex Binding
	Biological Process	Calcium Ion Transport Cellular Calcium Ion Homeostasis Response To Virus Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation Translational Elongation Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Activation Of Protein Kinase Activity
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Calcium Citrate Calcium Phosphate
Diseases
GWAS		Type 2 diabetes ( 25760438)	Chronic lymphocytic leukemia ( 28165464 24292274 23770605) Male-pattern baldness ( 27182965) Non-response to citalopram or escitalopram and depression ( 27622933)
Interacting Genes		30 interacting genes: APP ATP1A1 ATP1A2 BCL2L1 CALM1 DBN1 EEF1A1 EEF1A2 EEF1B2 EEF1D FANCA HSPB1 IKBKG LIG4 MCL1 MCPH1 MDM2 MLC1 NKX3-1 NOTCH3 PER2 PLK1 RBBP6 RPLP1 SNX6 SPP1 STEAP3 TRIP13 TUBB2A VHL	35 interacting genes: ANKRD13B ARF6 ASCC2 ATP5MF BRD7 C11orf58 C15orf39 CDIPT CDK2AP2 CLIC1 CSNK2A1 EEF1A1 GEMIN7 GSK3B LRIF1 MAP1LC3B MPC2 NSF NUDT21 NUDT3 PDCD4 PFDN1 PPP2CB PTN RCHY1 RPA2 RPLP2 RPS6KA6 SAT1 SGO1 TAB1 TPT1 TUBB2A UBE2D3 XRCC6
Entrez ID		7178	6176
HPRD ID		15979	01611
Ensembl ID		ENSG00000133112	ENSG00000137818
Uniprot IDs		A0A024RDY2 A0A0B4J2C3 A0A0P1J1R0 P13693	A0A024R608 P05386
PDB IDs		1YZ1 2HR9 3EBM 4Z9V 5O9L 5O9M	2LBF 4BEH 4V6X
Enriched GO Terms of Interacting Partners?
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