DKK1 and LRP6

  • Number of citations of the paper that reports this interaction (PubMedID 11357136)
  • 326
  • Data Source:
  • HPRD (in vivo)

DKK1

LRP6

Description dickkopf WNT signaling pathway inhibitor 1 LDL receptor related protein 6
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cerebrospinal fluid t-tau levels in normal cognition ( 29274321)
  • Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921)
  • Coronary artery calcification ( 23870195)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Heel bone mineral density ( 30598549)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Tandem gait ( 26219847)
Interacting Genes 8 interacting genes: CKAP4 DPP4 KREMEN1 KRTAP10-1 LRP5 LRP6 MDFI SMAD9 16 interacting genes: ANTXR1 ANTXR2 APOB ATP13A2 AXIN1 DKK1 DKK2 FZD5 FZD8 GSK3B LRRK2 MDK SERPINF1 TLNRD1 WNT1 WNT3A
Entrez ID 22943 4040
HPRD ID 05544 04617
Ensembl ID ENSG00000107984 ENSG00000070018
Uniprot IDs I1W660 O94907 O75581
PDB IDs 3S2K 3S8V 3SOQ 5FWW 5GJE 3S2K 3S8V 3S8Z 3S94 3SOB 3SOQ 3SOV 4A0P 4DG6 4NM5 4NM7 5AIR 5FWW 5GJE 6H15 6H16
Enriched GO Terms of Interacting Partners?
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