FKBP2 and ARFGEF1

Number of citations of the paper that reports this interaction (PubMedID 12606707)
17

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		FKBP2	ARFGEF1
Description		FKBP prolyl isomerase 2	ADP ribosylation factor guanine nucleotide exchange factor 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Golgi Membrane Nucleoplasm Nucleolus Golgi Apparatus Trans-Golgi Network Cytosol Nuclear Matrix Small Nuclear Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding	Guanyl-nucleotide Exchange Factor Activity ARF Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Myosin Binding Protein Kinase A Regulatory Subunit Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization	Exocytosis Golgi Organization Endomembrane System Organization Protein Transport Negative Regulation Of Actin Filament Polymerization Neuron Projection Development Regulation Of ARF Protein Signal Transduction Negative Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Protein Glycosylation In Golgi Positive Regulation Of Wound Healing Regulation Of Establishment Of Cell Polarity
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 28067908)	Chronic central serous retinopathy ( 30073298) Hearing function ( 25060954) Hip circumference adjusted for BMI ( 28552196)
Interacting Genes		13 interacting genes: ARFGEF1 BAG6 BARD1 C1QC EPB41 EPB41L2 MAPK3 RAB3C RAB6A RAP2A UBQLN1 UBQLN4 VAMP2	5 interacting genes: ARFGEF2 CTNNB1 DPY30 FKBP2 MYO9B
Entrez ID		2286	10565
HPRD ID		01742	09163
Ensembl ID		ENSG00000173486	ENSG00000066777
Uniprot IDs		P26885 Q53XJ5	A0A024R7X0 Q9Y6D6
PDB IDs		2PBC 4NNR	3LTL 5EE5 5J5C
Enriched GO Terms of Interacting Partners?
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