ARFGEF1

Description		ADP ribosylation factor guanine nucleotide exchange factor 1
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GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Nucleolus Golgi Apparatus Trans-Golgi Network Cytosol Nuclear Matrix Small Nuclear Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity ARF Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Myosin Binding Protein Kinase A Regulatory Subunit Binding
	Biological Process	Exocytosis Golgi Organization Endomembrane System Organization Protein Transport Negative Regulation Of Actin Filament Polymerization Neuron Projection Development Regulation Of ARF Protein Signal Transduction Negative Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Protein Glycosylation In Golgi Positive Regulation Of Wound Healing Regulation Of Establishment Of Cell Polarity
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Diseases
GWAS		Chronic central serous retinopathy ( 30073298) Hearing function ( 25060954) Hip circumference adjusted for BMI ( 28552196)
Interacting Genes		5 interacting genes: ARFGEF2 CTNNB1 DPY30 FKBP2 MYO9B
Entrez ID		10565
HPRD ID		09163
Ensembl ID		ENSG00000066777
Uniprot IDs		A0A024R7X0 Q9Y6D6
PDB IDs		3LTL 5EE5 5J5C
Enriched GO Terms of Interacting Partners?
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