ARFGEF1 and FKBP2

Number of citations of the paper that reports this interaction (PubMedID 12606707)
17

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		ARFGEF1	FKBP2
Description		ADP ribosylation factor guanine nucleotide exchange factor 1	FKBP prolyl isomerase 2
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GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Nucleolus Golgi Apparatus Trans-Golgi Network Cytosol Nuclear Matrix Small Nuclear Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity ARF Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Myosin Binding Protein Kinase A Regulatory Subunit Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding
	Biological Process	Exocytosis Golgi Organization Endomembrane System Organization Protein Transport Negative Regulation Of Actin Filament Polymerization Neuron Projection Development Regulation Of ARF Protein Signal Transduction Negative Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Protein Glycosylation In Golgi Positive Regulation Of Wound Healing Regulation Of Establishment Of Cell Polarity	Protein Peptidyl-prolyl Isomerization
Pathways
Drugs
Diseases
GWAS		Chronic central serous retinopathy ( 30073298) Hearing function ( 25060954) Hip circumference adjusted for BMI ( 28552196)	Crohn's disease ( 28067908)
Interacting Genes		5 interacting genes: ARFGEF2 CTNNB1 DPY30 FKBP2 MYO9B	13 interacting genes: ARFGEF1 BAG6 BARD1 C1QC EPB41 EPB41L2 MAPK3 RAB3C RAB6A RAP2A UBQLN1 UBQLN4 VAMP2
Entrez ID		10565	2286
HPRD ID		09163	01742
Ensembl ID		ENSG00000066777	ENSG00000173486
Uniprot IDs		A0A024R7X0 Q9Y6D6	P26885 Q53XJ5
PDB IDs		3LTL 5EE5 5J5C	2PBC 4NNR
Enriched GO Terms of Interacting Partners?
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