PUF60 and PTBP2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		PUF60	PTBP2
Description		poly(U) binding splicing factor 60	polypyrimidine tract binding protein 2
Image
GO Annotations	Cellular Component	Nucleoplasm Cell Junction	Nucleus Spliceosomal Complex Growth Cone Neuronal Cell Body
	Molecular Function	DNA Binding RNA Binding Protein Binding Identical Protein Binding Cadherin Binding	RNA Binding MRNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Apoptotic Process	MRNA Splice Site Selection Regulation Of Translation Spinal Cord Development Cerebellum Development Negative Regulation Of RNA Splicing Regulation Of RNA Splicing Regulation Of Neural Precursor Cell Proliferation
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Anorexia nervosa ( 31308545) Autism spectrum disorder ( 30804558) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically inactive individuals ( 28448500) Chronotype ( 30696823) Headache ( 29397368) Hip circumference ( 25673412) Number of sexual partners ( 30643258) Reaction time ( 29844566) Regular attendance at a pub or social club ( 29970889) Schizophrenia ( 19571811 22688191) Smoking status (ever vs never smokers) ( 30643258) Trunk fat mass adjusted for trunk lean mass ( 30944420) Waist circumference ( 25673412)
Interacting Genes		34 interacting genes: ARL8A BORCS5 CACNA1A CCNC CD101 CHD3 CPEB2 ERG FBXO7 FHL2 FUBP1 H1-2 ID3 IQCN KHDC4 LARP7 MED28 PCBP1 PPP1R16A PTBP2 QRICH1 RAD23B RAP1GDS1 SAP30BP SDCBP SIAH1 SNRPF SRSF11 U2AF2 UBE2I UPF2 VIM YWHAG ZG16	20 interacting genes: CALCOCO2 EIF5A2 ELAVL1 GBP1 GOLGA2 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 PCBP3 PKN2 PUF60 QKI RBM10 RBM4 SNRPA TOM1
Entrez ID		22827	58155
HPRD ID		18051	12233
Ensembl ID		ENSG00000179950	ENSG00000117569
Uniprot IDs		Q9UHX1	B4DSS8 B4DSU5 Q9UKA9
PDB IDs		2DNY 2KXF 2KXH 2QFJ 3DXB 3UE2 3US5 3UWT 5KVY 5KW1 5KW6 5KWQ	2CQ1 2MJU 4CQ1
Enriched GO Terms of Interacting Partners?
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