PTBP2 and MATR3

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		PTBP2	MATR3
Description		polypyrimidine tract binding protein 2	matrin 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Growth Cone Neuronal Cell Body	Nucleus Nuclear Inner Membrane Membrane Nuclear Matrix
	Molecular Function	RNA Binding MRNA Binding	RNA Binding MRNA Binding Structural Molecule Activity Protein Binding Zinc Ion Binding MiRNA Binding Identical Protein Binding
	Biological Process	MRNA Splice Site Selection Regulation Of Translation Spinal Cord Development Cerebellum Development Negative Regulation Of RNA Splicing Regulation Of RNA Splicing Regulation Of Neural Precursor Cell Proliferation	Activation Of Innate Immune Response Heart Valve Development Ventricular Septum Development Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Innate Immune Response
Pathways
Drugs
Diseases			Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
GWAS		Anorexia nervosa ( 31308545) Autism spectrum disorder ( 30804558) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically inactive individuals ( 28448500) Chronotype ( 30696823) Headache ( 29397368) Hip circumference ( 25673412) Number of sexual partners ( 30643258) Reaction time ( 29844566) Regular attendance at a pub or social club ( 29970889) Schizophrenia ( 19571811 22688191) Smoking status (ever vs never smokers) ( 30643258) Trunk fat mass adjusted for trunk lean mass ( 30944420) Waist circumference ( 25673412)	Body mass index ( 26426971) Metabolite levels ( 23823483)
Interacting Genes		20 interacting genes: CALCOCO2 EIF5A2 ELAVL1 GBP1 GOLGA2 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 PCBP3 PKN2 PUF60 QKI RBM10 RBM4 SNRPA TOM1	18 interacting genes: AIMP2 AKTIP CALM1 EGFR ERG GFI1B HNRNPK LMNA PCBP1 PTBP2 RASD1 SNAP23 SNRNP200 SRPK2 TNFRSF21 TRAF6 TTF2 UBE2I
Entrez ID		58155	9782
HPRD ID		12233	05270
Ensembl ID		ENSG00000117569	ENSG00000015479
Uniprot IDs		B4DSS8 B4DSU5 Q9UKA9	A0A0R4J2E8 B3KM87 B4DF66 P43243 Q9H4N1
PDB IDs		2CQ1 2MJU 4CQ1
Enriched GO Terms of Interacting Partners?
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