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E2F4 and TFDP1
Number of citations of the paper that reports this interaction (PubMedID
27705803
)
42
Data Source:
BioGRID
(affinity chromatography technology, pull down)
HPRD
(in vitro)
E2F4
TFDP1
Description
E2F transcription factor 4
transcription factor Dp-1
Image
GO Annotations
Cellular Component
Nuclear Chromatin
Cell
Nucleus
Nucleoplasm
Cytoplasm
RNA Polymerase II Transcription Factor Complex
Nuclear Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
RNA Polymerase II Transcription Factor Complex
Molecular Function
RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Bacterial-type RNA Polymerase Transcriptional Activator Activity, Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Protein Domain Specific Binding
Sequence-specific DNA Binding
Protein Dimerization Activity
Promoter-specific Chromatin Binding
RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Proximal Promoter Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Transcription Coactivator Activity
Protein Binding
Transcription Factor Binding
Protein Domain Specific Binding
Biological Process
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Epithelial Cell Development
Cell Volume Homeostasis
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Blood Circulation
Animal Organ Morphogenesis
Regulation Of Cell Proliferation
Motile Cilium Assembly
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Cycle
Centriole Assembly
Multi-ciliated Epithelial Cell Differentiation
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Epidermis Development
Anoikis
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of G0 To G1 Transition
Negative Regulation Of Fat Cell Proliferation
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Regulation Of DNA Biosynthetic Process
Pathways
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Cyclin E associated events during G1/S transition
G1/S-Specific Transcription
G1/S-Specific Transcription
Cyclin D associated events in G1
Cyclin A:Cdk2-associated events at S phase entry
Activation of NOXA and translocation to mitochondria
Inhibition of replication initiation of damaged DNA by RB1/E2F1
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
Activation of PUMA and translocation to mitochondria
G0 and Early G1
Pre-NOTCH Transcription and Translation
Pre-NOTCH Transcription and Translation
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Oxidative Stress Induced Senescence
Oncogene Induced Senescence
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Cyclin E associated events during G1/S transition
G1/S-Specific Transcription
G1/S-Specific Transcription
Cyclin D associated events in G1
Cyclin A:Cdk2-associated events at S phase entry
Transcriptional Regulation by E2F6
Transcriptional regulation of granulopoiesis
Transcriptional regulation of granulopoiesis
Drugs
Diseases
GWAS
Height (
31562340
)
Mild influenza (H1N1) infection (
26379185
)
Interacting Genes
29 interacting genes:
AP3S2
ARID3A
ATAD2
BRCA1
CHMP2A
CHUK
FHL2
HCFC1
ID3
IKBKB
LRRK2
MFHAS1
MGA
NDN
NOLC1
PCM1
POLR1D
RB1
RBL1
RBL2
RNF144A
RYBP
SMAD2
SMAD3
SPIB
TFDP1
TFDP2
TRRAP
XPO1
17 interacting genes:
CDK1
CDK2
CDK6
CDKN2A
CREBBP
E2F1
E2F2
E2F3
E2F4
E2F5
E2F6
NPDC1
SERTAD2
SIAH1
SOCS3
TP53
TP53BP1
Entrez ID
1874
7027
HPRD ID
02806
01792
Ensembl ID
ENSG00000205250
ENSG00000198176
Uniprot IDs
Q16254
A0A024RDY4
Q14186
PDB IDs
1CF7
5TUU
2AZE
5GOW
5TUU
5TUV
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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