TFDP1 and SERTAD2

Number of citations of the paper that reports this interaction (PubMedID 11331592)
35

Data Source:
HPRD (in vitro)

		TFDP1	SERTAD2
Description		transcription factor Dp-1	SERTA domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol RNA Polymerase II Transcription Factor Complex	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding	Transcription Coactivator Activity
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Epidermis Development Anoikis Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of G0 To G1 Transition Negative Regulation Of Fat Cell Proliferation Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of DNA Biosynthetic Process	Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated
Pathways		Activation of NOXA and translocation to mitochondria Inhibition of replication initiation of damaged DNA by RB1/E2F1 Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 Activation of PUMA and translocation to mitochondria G0 and Early G1 Pre-NOTCH Transcription and Translation Pre-NOTCH Transcription and Translation SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Oxidative Stress Induced Senescence Oncogene Induced Senescence TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Cyclin E associated events during G1/S transition G1/S-Specific Transcription G1/S-Specific Transcription Cyclin D associated events in G1 Cyclin A:Cdk2-associated events at S phase entry Transcriptional Regulation by E2F6 Transcriptional regulation of granulopoiesis Transcriptional regulation of granulopoiesis
Drugs
Diseases
GWAS		Height ( 31562340) Mild influenza (H1N1) infection ( 26379185)	Antisaccade task score ( 31596458) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 29403010 27863252) Monocyte percentage of white cells ( 27863252) Red cell distribution width ( 27863252 28957414) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Visceral fat ( 22589738)
Interacting Genes		17 interacting genes: CDK1 CDK2 CDK6 CDKN2A CREBBP E2F1 E2F2 E2F3 E2F4 E2F5 E2F6 NPDC1 SERTAD2 SIAH1 SOCS3 TP53 TP53BP1	8 interacting genes: CEP68 CREBBP E2F1 KAT2B SUPT7L TFDP1 TRIM28 XPO1
Entrez ID		7027	9792
HPRD ID		01792	18040
Ensembl ID		ENSG00000198176	ENSG00000179833
Uniprot IDs		A0A024RDY4 Q14186	Q14140
PDB IDs		2AZE 5GOW 5TUU 5TUV
Enriched GO Terms of Interacting Partners?
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