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E2F4 and RBL1
Number of citations of the paper that reports this interaction (PubMedID
12150994
)
167
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology)
HPRD
(in vitro, in vivo)
E2F4
RBL1
Description
E2F transcription factor 4
RB transcriptional corepressor like 1
Image
GO Annotations
Cellular Component
Nuclear Chromatin
Cell
Nucleus
Nucleoplasm
Cytoplasm
RNA Polymerase II Transcription Factor Complex
Chromatin
Nucleoplasm
Transcription Factor Complex
Molecular Function
RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Bacterial-type RNA Polymerase Transcriptional Activator Activity, Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Protein Domain Specific Binding
Sequence-specific DNA Binding
Protein Dimerization Activity
Promoter-specific Chromatin Binding
RNA Polymerase II Regulatory Region DNA Binding
RNA Polymerase II Activating Transcription Factor Binding
Protein Binding
Transcription Factor Binding
Promoter-specific Chromatin Binding
Biological Process
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Epithelial Cell Development
Cell Volume Homeostasis
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Blood Circulation
Animal Organ Morphogenesis
Regulation Of Cell Proliferation
Motile Cilium Assembly
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Cycle
Centriole Assembly
Multi-ciliated Epithelial Cell Differentiation
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Cell Cycle
Regulation Of Mitotic Cell Cycle
Negative Regulation Of Gene Expression
Viral Process
Cell Differentiation
Regulation Of Lipid Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Division
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Cellular Senescence
Pathways
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Cyclin E associated events during G1/S transition
G1/S-Specific Transcription
G1/S-Specific Transcription
Cyclin D associated events in G1
Cyclin A:Cdk2-associated events at S phase entry
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
G1/S-Specific Transcription
Cyclin D associated events in G1
Drugs
Diseases
GWAS
Height (
25429064
)
Red cell distribution width (
28957414
)
Interacting Genes
29 interacting genes:
AP3S2
ARID3A
ATAD2
BRCA1
CHMP2A
CHUK
FHL2
HCFC1
ID3
IKBKB
LRRK2
MFHAS1
MGA
NDN
NOLC1
PCM1
POLR1D
RB1
RBL1
RBL2
RNF144A
RYBP
SMAD2
SMAD3
SPIB
TFDP1
TFDP2
TRRAP
XPO1
54 interacting genes:
AOX1
BEGAIN
BRCA1
BRF1
CCNA1
CCNA2
CCND1
CCNE1
CDK2
CDK4
CDK6
CEBPA
CREG1
DGKZ
DHX30
DYRK1A
E2F1
E2F4
E2F5
EPHA2
FN1
GOLGA2
HDAC1
ID2
IRF3
KDM5A
KMT5C
LAMB2
MAPK6
MCM7
MYBL2
MYC
NR2E3
NR4A1
NUCB1
PHB
PLSCR1
PPP2R3A
RBBP8
RBBP9
RINT1
SMAD2
SMAD3
SMAD4
SMARCA4
SNRPD3
SNW1
SP1
SUV39H1
TAF1
TOP1
TP53BP1
TSC22D2
USP4
Entrez ID
1874
5933
HPRD ID
02806
00312
Ensembl ID
ENSG00000205250
ENSG00000080839
Uniprot IDs
Q16254
P28749
PDB IDs
1CF7
5TUU
1H28
4YOO
4YOS
4YOZ
5TUV
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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