DDX6 and BIRC7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		DDX6	BIRC7
Description		DEAD-box helicase 6	baculoviral IAP repeat containing 7
Image
GO Annotations	Cellular Component	Heterochromatin P-body Outer Dense Fiber Nucleus Nucleolus Cytoplasm Mitochondrion Cytosol Cytoplasmic Stress Granule Membrane RISC Complex Chromatoid Body Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm Concave Side Of Sperm Head Sperm Annulus	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol
	Molecular Function	RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Protein Domain Specific Binding Cadherin Binding	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Enzyme Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Viral RNA Genome Packaging Stem Cell Population Maintenance Cytoplasmic MRNA Processing Body Assembly Stress Granule Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Negative Regulation Of Neuron Differentiation Spermatid Differentiation	Apoptotic Process Activation Of JUN Kinase Activity Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Regulation Of Cell Proliferation Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Natural Killer Cell Apoptotic Process Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Pathways		mRNA decay by 5' to 3' exoribonuclease
Drugs		D-tartaric acid
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 30929738 31619474) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Blood protein levels ( 30072576) Celiac disease ( 22057235) Celiac disease and Rheumatoid arthritis ( 26546613) Celiac disease or Rheumatoid arthritis ( 21383967) Diffuse cutaneous systemic sclerosis ( 24387989) Height ( 25429064) Hip minimal joint space width ( 27701424) Multiple sclerosis ( 31604244) Non-albumin protein levels ( 29403010) Primary biliary cholangitis ( 28425483) Primary biliary cirrhosis ( 22961000) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Systemic lupus erythematosus ( 28714469 19838195) Systemic sclerosis ( 24387989 31672989) Vitiligo ( 22951725)
Interacting Genes		29 interacting genes: BEND7 BIRC7 CALCOCO2 CEP70 CNOT1 EDC3 EIF4ENIF1 ENTR1 GOLGA2 IKZF1 KLC4 KRT40 KRTAP10-3 KRTAP10-8 NONO PNMA5 RBM14 RUNDC3A SIPA1L2 SRPK2 STAT1 TCF4 TLE5 TRIM27 TRIM37 U2AF2 VPS52 ZBTB8A ZNF24	17 interacting genes: CASP3 CASP7 CASP9 DDX6 DIABLO FAM124B HTRA2 PHF1 POLR1C PTCD3 TLE5 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2I UBE2K
Entrez ID		1656	79444
HPRD ID		02638	05761
Ensembl ID		ENSG00000110367	ENSG00000101197
Uniprot IDs		B2R858 P26196	Q96CA5
PDB IDs		1VEC 2WAX 2WAY 4CRW 4CT4 4CT5 5ANR 6F9S 6S8S	1OXN 1OXQ 1OY7 1TW6 2I3H 2I3I 3F7G 3F7H 3F7I 3GT9 3GTA 3UW5 4AUQ
Enriched GO Terms of Interacting Partners?
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