DDX6 and KLC4

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		DDX6	KLC4
Description		DEAD-box helicase 6	kinesin light chain 4
Image			No pdb structure
GO Annotations	Cellular Component	Heterochromatin P-body Outer Dense Fiber Nucleus Nucleolus Cytoplasm Mitochondrion Cytosol Cytoplasmic Stress Granule Membrane RISC Complex Chromatoid Body Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm Concave Side Of Sperm Head Sperm Annulus	Cytoplasm Kinesin Complex Microtubule
	Molecular Function	RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Protein Domain Specific Binding Cadherin Binding	Microtubule Motor Activity Protein Binding
	Biological Process	Viral RNA Genome Packaging Stem Cell Population Maintenance Cytoplasmic MRNA Processing Body Assembly Stress Granule Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Negative Regulation Of Neuron Differentiation Spermatid Differentiation
Pathways		mRNA decay by 5' to 3' exoribonuclease	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs		D-tartaric acid
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 30929738 31619474) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Blood protein levels ( 30072576) Celiac disease ( 22057235) Celiac disease and Rheumatoid arthritis ( 26546613) Celiac disease or Rheumatoid arthritis ( 21383967) Diffuse cutaneous systemic sclerosis ( 24387989) Height ( 25429064) Hip minimal joint space width ( 27701424) Multiple sclerosis ( 31604244) Non-albumin protein levels ( 29403010) Primary biliary cholangitis ( 28425483) Primary biliary cirrhosis ( 22961000) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Systemic lupus erythematosus ( 28714469 19838195) Systemic sclerosis ( 24387989 31672989) Vitiligo ( 22951725)
Interacting Genes		29 interacting genes: BEND7 BIRC7 CALCOCO2 CEP70 CNOT1 EDC3 EIF4ENIF1 ENTR1 GOLGA2 IKZF1 KLC4 KRT40 KRTAP10-3 KRTAP10-8 NONO PNMA5 RBM14 RUNDC3A SIPA1L2 SRPK2 STAT1 TCF4 TLE5 TRIM27 TRIM37 U2AF2 VPS52 ZBTB8A ZNF24	26 interacting genes: ABI3 AKAP9 APP CASK CEP57L1 COIL DDX6 KATNAL1 KLC2 KPNA2 KRT13 KRT15 KRT31 MEOX2 NDEL1 NECAB2 PCM1 PDE4DIP PKP2 PRC1 RBM14 SLC16A9 TADA2A USHBP1 YWHAE YWHAZ
Entrez ID		1656	89953
HPRD ID		02638	13932
Ensembl ID		ENSG00000110367	ENSG00000137171
Uniprot IDs		B2R858 P26196	A0A024RCZ8 Q9NSK0
PDB IDs		1VEC 2WAX 2WAY 4CRW 4CT4 4CT5 5ANR 6F9S 6S8S
Enriched GO Terms of Interacting Partners?
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