CTNND1 and KCTD6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CTNND1	KCTD6
Description		catenin delta 1	potassium channel tetramerization domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Zonula Adherens Catenin Complex Lamellipodium Growth Cone Midbody Dendritic Spine Extracellular Exosome Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse Postsynaptic Density, Intracellular Component	Cytosol M Band
	Molecular Function	Signaling Receptor Binding Protein Binding Protein Kinase Binding Cadherin Binding	Protein Binding Ankyrin Binding Identical Protein Binding Cullin Family Protein Binding
	Biological Process	Cell-cell Junction Assembly Brain Development Wnt Signaling Pathway Adherens Junction Organization Entry Of Bacterium Into Host Cell Cell-cell Adhesion Mediated By Cadherin Protein Stabilization Negative Regulation Of Canonical Wnt Signaling Pathway Cell-cell Adhesion Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Growth Post-translational Protein Modification Negative Regulation Of Smoothened Signaling Pathway Protein Homooligomerization
Pathways		Adherens junctions interactions VEGFR2 mediated vascular permeability InlA-mediated entry of Listeria monocytogenes into host cells	RUNX1 regulates estrogen receptor mediated transcription Neddylation Estrogen-dependent gene expression Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Household income (MTAG) ( 31844048) Neuroticism ( 29255261) Parkinson's disease ( 27182965) Pulse pressure ( 27841878 30578418) Schizophrenia ( 25056061 29483656) Systolic blood pressure ( 27841878)	Hepcidin/transferrin saturation ratio ( 27846281) Systemic lupus erythematosus ( 28714469) vWF levels ( 30586737)
Interacting Genes		29 interacting genes: ACTA1 APP CDH1 CDH24 CDH3 CDH5 COL17A1 CTTN EGFR ERBIN FER GRIK2 GSK3B JUP KCTD6 LCK MTNR1B MUC1 PLPP3 PSEN1 PTPN6 PTPRJ PTPRM RPS6KA3 SNCA SRC SUMO2 YWHAG ZBTB33	17 interacting genes: ACTN1 ACTN3 ANK1 C8orf33 CDC23 CTNND1 EHHADH FAM124B GOLGA8EP GOLGA8F GRB7 GSDMD LNX1 PPIG PRPF31 SDCBP ZCCHC10
Entrez ID		1500	200845
HPRD ID		03026	13769
Ensembl ID		ENSG00000198561	ENSG00000168301
Uniprot IDs		O60716	Q8NC69
PDB IDs		3L6X 3L6Y
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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