CTNND1 and PTPRM

Number of citations of the paper that reports this interaction (PubMedID 15588985)
63

Data Source:
BioGRID (enzymatic study)
HPRD (in vitro, in vivo)

		CTNND1	PTPRM
Description		catenin delta 1	protein tyrosine phosphatase receptor type M
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Zonula Adherens Catenin Complex Lamellipodium Growth Cone Midbody Dendritic Spine Extracellular Exosome Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse Postsynaptic Density, Intracellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Adherens Junction Lamellipodium Perinuclear Region Of Cytoplasm
	Molecular Function	Signaling Receptor Binding Protein Binding Protein Kinase Binding Cadherin Binding	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Identical Protein Binding Cadherin Binding
	Biological Process	Cell-cell Junction Assembly Brain Development Wnt Signaling Pathway Adherens Junction Organization Entry Of Bacterium Into Host Cell Cell-cell Adhesion Mediated By Cadherin Protein Stabilization Negative Regulation Of Canonical Wnt Signaling Pathway Cell-cell Adhesion Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels	Negative Regulation Of Endothelial Cell Proliferation Protein Dephosphorylation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Signal Transduction Negative Regulation Of Endothelial Cell Migration Retina Layer Formation Negative Regulation Of Angiogenesis Neuron Projection Development Retinal Ganglion Cell Axon Guidance Peptidyl-tyrosine Dephosphorylation Response To Drug Positive Regulation Of Blood Vessel Diameter
Pathways		Adherens junctions interactions VEGFR2 mediated vascular permeability InlA-mediated entry of Listeria monocytogenes into host cells
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Household income (MTAG) ( 31844048) Neuroticism ( 29255261) Parkinson's disease ( 27182965) Pulse pressure ( 27841878 30578418) Schizophrenia ( 25056061 29483656) Systolic blood pressure ( 27841878)	Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Dialysis-related mortality ( 21546767) Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243) Glucose homeostasis traits ( 25524916) Hippocampal volume ( 29860282) Huntington's disease progression ( 28642124) Iris heterochromicity ( 30895295) Lateral ventricle temporal horn volume ( 31530798) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Recurrence of mild malaria attacks ( 31667592) Response to methotrexate in rheumatoid arthritis ( 24583629) Sitting height ratio ( 25865494)
Interacting Genes		29 interacting genes: ACTA1 APP CDH1 CDH24 CDH3 CDH5 COL17A1 CTTN EGFR ERBIN FER GRIK2 GSK3B JUP KCTD6 LCK MTNR1B MUC1 PLPP3 PSEN1 PTPN6 PTPRJ PTPRM RPS6KA3 SNCA SRC SUMO2 YWHAG ZBTB33	11 interacting genes: BCCIP CDH1 CTNNB1 CTNND1 IQGAP1 PCSK5 PPFIBP1 PTPRA PTPRK PTPRS RACK1
Entrez ID		1500	5797
HPRD ID		03026	01479
Ensembl ID		ENSG00000198561	ENSG00000173482
Uniprot IDs		O60716	P28827
PDB IDs		3L6X 3L6Y	1RPM 2C9A 2V5Y
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?