KCTD6 and FAM124B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KCTD6	FAM124B
Description		potassium channel tetramerization domain containing 6	family with sequence similarity 124 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol M Band	Nucleoplasm Mitochondrion
	Molecular Function	Protein Binding Ankyrin Binding Identical Protein Binding Cullin Family Protein Binding	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Growth Post-translational Protein Modification Negative Regulation Of Smoothened Signaling Pathway Protein Homooligomerization
Pathways		RUNX1 regulates estrogen receptor mediated transcription Neddylation Estrogen-dependent gene expression Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Hepcidin/transferrin saturation ratio ( 27846281) Systemic lupus erythematosus ( 28714469) vWF levels ( 30586737)	Bitter beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Familial squamous cell lung carcinoma ( 29924316)
Interacting Genes		17 interacting genes: ACTN1 ACTN3 ANK1 C8orf33 CDC23 CTNND1 EHHADH FAM124B GOLGA8EP GOLGA8F GRB7 GSDMD LNX1 PPIG PRPF31 SDCBP ZCCHC10	29 interacting genes: ADAMTSL4 BIRC7 CARD9 CCDC85B EFEMP2 GOLGA2 KCTD6 KCTD9 KIAA1958 KRT19 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 LZTS2 MDFI MKRN3 NOTCH2NLA RBPMS RINT1 SSX2IP TCF4 TLE5 TRIM37 TRIM54 TRIP6 USHBP1
Entrez ID		200845	79843
HPRD ID		13769	08663
Ensembl ID		ENSG00000168301	ENSG00000124019
Uniprot IDs		Q8NC69	Q9H5Z6
PDB IDs
Enriched GO Terms of Interacting Partners?
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