CRYAA and NTAQ1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CRYAA	NTAQ1
Description		crystallin alpha A	N-terminal glutamine amidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex	Nucleus Cytosol
	Molecular Function	Structural Molecule Activity Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding Metal Ion Binding Unfolded Protein Binding	Protein Binding Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity
	Biological Process	Visual Perception Negative Regulation Of Intracellular Transport Protein Refolding Negative Regulation Of Apoptotic Process Protein Stabilization Response To Stimulus	Cellular Protein Modification Process
Pathways
Drugs
Diseases
GWAS		Age-related nuclear cataracts ( 24951543) Diastolic blood pressure ( 28135244 27841878 28739976 27618452) Metabolite levels ( 23823483) Systolic blood pressure ( 27841878 28739976 27618452)
Interacting Genes		17 interacting genes: ALB BCL2L1 CRYAB CRYBA1 CRYBB2 CRYGC CRYGD CRYZ CS GORASP2 HSPB1 HSPB2 LALBA MIP NTAQ1 SDCBP SPG21	106 interacting genes: ACTB ACTG1 AMOT AMOTL2 APIP ASL BLMH BLOC1S6 C1orf50 CAPN3 CBFA2T2 CBS CBY2 CCDC102B CCDC184 CDA CDR2 CEP55 COG6 COIL CRYAA CTBP1 CTH DAB1 DCTPP1 DHPS DNM2 EDARADD EIF2B1 ETV6 FTH1 GAS7 GMCL1 GMDS GNMT GOLGA2 HPRT1 HSD17B14 IKZF3 JAKMIP2 JUP KASH5 KCNH1 KCTD1 KLHL12 KRT31 KRTAP10-5 KRTAP10-7 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LMNA LNX2 LONRF1 LZTFL1 LZTS2 MAGEA11 MARCHF10 MDFI MIF MIOS MTUS2 NAGK NCOA5 NECAB2 NME1 NPL NT5C1A NUDT14 PCBD1 PNMA1 PNMA5 PPCDC PRMT1 PRPS2 PSME3 PTS PYGM RABAC1 RBBP8 RBPMS ROPN1 RPIA SEPTIN3 SFN SIAH1 SMN1 SSX2IP STX11 TCL1A THAP1 TLE5 TMEM239 TNR TOLLIP TRAF1 TRIM27 TRIM54 TRIP13 TSC22D1 VAC14 VCP XIAP ZBTB8A ZNF341
Entrez ID		1409	55093
HPRD ID		00427	07653
Ensembl ID		ENSG00000160202	ENSG00000156795
Uniprot IDs		A0A140G945 P02489	A0A3B3ITD7 A0A3B3ITI2 E5RHC2 Q96HA8
PDB IDs			3C9Q 4W79
Enriched GO Terms of Interacting Partners?
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