SWSAP1 and RAD51B

Number of citations of the paper that reports this interaction (PubMedID 21965664)
31

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SWSAP1	RAD51B
Description		SWIM-type zinc finger 7 associated protein 1	RAD51 paralog B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Shu Complex	Nucleus Nucleoplasm Replication Fork Rad51B-Rad51C-Rad51D-XRCC2 Complex
	Molecular Function	Single-stranded DNA Binding Protein Binding ATPase Activity	Four-way Junction DNA Binding DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination Protein Stabilization	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination Reciprocal Meiotic Recombination Blood Coagulation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Pathways			HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Presynaptic phase of homologous DNA pairing and strand exchange Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Advanced age-related macular degeneration ( 26691988) Adverse response to drug ( 30420678) Age-related macular degeneration ( 23455636) Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Asthma ( 31361310 30929738 27182965 31619474) Asthma (childhood onset) ( 31036433 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 29059683) Breast cancer (male) ( 23001122) Cancer (pleiotropy) ( 27197191) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Granulocyte count ( 27863252) Heel bone mineral density ( 30598549) Height ( 31562340) Macular thickness ( 30535121) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean platelet volume ( 27863252) Medication use (thyroid preparations) ( 31015401) Monoclonal gammopathy of undetermined significance ( 30737484) Multiple sclerosis ( 31604244) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Nose size ( 27182965) Platelet count ( 27863252) Plateletcrit ( 27863252) Primary biliary cholangitis ( 26394269) Primary biliary cirrhosis ( 22961000) Prostate cancer ( 23535732) Red blood cell count ( 27863252) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systemic lupus erythematosus ( 26502338 28714469) Type 2 diabetes nephropathy ( 30566433) White blood cell count ( 27863252)
Interacting Genes		7 interacting genes: A2M RAD51 RAD51B RAD51C RAD51D XRCC3 ZSWIM7	10 interacting genes: ABL1 FAM9B H1-0 H2BC8 H3C1 H4C14 RAD51 RAD51C RAD51D SWSAP1
Entrez ID		126074	5890
HPRD ID		08179	04255
Ensembl ID		ENSG00000173928	ENSG00000182185
Uniprot IDs		Q6NVH7	A0A024R656 C9JYJ0 O15315
PDB IDs
Enriched GO Terms of Interacting Partners?
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