CBX3 and MGA

Number of citations of the paper that reports this interaction (PubMedID 20850016)
295

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		CBX3	MGA
Description		chromobox 3	MAX dimerization protein MGA
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Chromosome, Centromeric Region Nuclear Chromosome, Telomeric Region Chromatin Nucleus Nuclear Envelope Nuclear Inner Membrane Nucleoplasm Nuclear Euchromatin Nuclear Heterochromatin Spindle Nuclear Pericentric Heterochromatin Senescence-associated Heterochromatin Focus Site Of DNA Damage	Nuclear Chromatin Nucleus Nucleoplasm MLL1 Complex
	Molecular Function	Protein Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Histone Methyltransferase Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity
	Biological Process	Chromatin Remodeling Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated Rhythmic Process Negative Regulation Of G0 To G1 Transition Cellular Response To Dexamethasone Stimulus	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G0 To G1 Transition
Pathways		ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression RNA Polymerase I Promoter Escape Transcriptional Regulation by E2F6	Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Feeling nervous ( 29500382) Lung function (FEV1/FVC) ( 28166213 30804560) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		32 interacting genes: ARL5A ATXN7L2 AURKA AURKB BARD1 CACNB4 CBX1 CBX5 DNMT3B DSN1 H1-4 H3-4 H3C1 H4C1 HECW2 HIPK2 KLF11 L3MBTL1 LBR MGA MIS12 MKI67 NSD3 NSL1 PIM1 SP100 TAF4 TRIM24 TRIM28 VHL ZNF10 ZNF496	8 interacting genes: CBX3 E2F1 E2F3 E2F4 H3-4 LSM8 MAX SMAD1
Entrez ID		11335	23269
HPRD ID		05130	19055
Ensembl ID		ENSG00000122565	ENSG00000174197
Uniprot IDs		A4D177 Q13185	Q8IWI9
PDB IDs		2L11 3DM1 3KUP 3TZD 5T1I
Enriched GO Terms of Interacting Partners?
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