CBX3 and ATXN7L2

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CBX3	ATXN7L2
Description		chromobox 3	ataxin 7 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Chromosome, Centromeric Region Nuclear Chromosome, Telomeric Region Chromatin Nucleus Nuclear Envelope Nuclear Inner Membrane Nucleoplasm Nuclear Euchromatin Nuclear Heterochromatin Spindle Nuclear Pericentric Heterochromatin Senescence-associated Heterochromatin Focus Site Of DNA Damage
	Molecular Function	Protein Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Histone Methyltransferase Binding
	Biological Process	Chromatin Remodeling Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated Rhythmic Process Negative Regulation Of G0 To G1 Transition Cellular Response To Dexamethasone Stimulus
Pathways		ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression RNA Polymerase I Promoter Escape Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 20125088)
Interacting Genes		32 interacting genes: ARL5A ATXN7L2 AURKA AURKB BARD1 CACNB4 CBX1 CBX5 DNMT3B DSN1 H1-4 H3-4 H3C1 H4C1 HECW2 HIPK2 KLF11 L3MBTL1 LBR MGA MIS12 MKI67 NSD3 NSL1 PIM1 SP100 TAF4 TRIM24 TRIM28 VHL ZNF10 ZNF496	4 interacting genes: CBX3 LAMB1 MDFI PPP2R3A
Entrez ID		11335	127002
HPRD ID		05130	12506
Ensembl ID		ENSG00000122565	ENSG00000162650
Uniprot IDs		A4D177 Q13185	Q5T6C5
PDB IDs		2L11 3DM1 3KUP 3TZD 5T1I
Enriched GO Terms of Interacting Partners?
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