FRS3 and RND1

Number of citations of the paper that reports this interaction (PubMedID 15738000)
14

Data Source:
HPRD (in vitro)

		FRS3	RND1
Description		fibroblast growth factor receptor substrate 3	Rho family GTPase 1
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GO Annotations	Cellular Component	Plasma Membrane	Cytoplasm Cytosol Plasma Membrane Adherens Junction Cell Cortex Actin Cytoskeleton Cytoplasmic Vesicle Cell Division Site Intracellular Membrane-bounded Organelle
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Identical Protein Binding	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	MAPK Cascade Signal Transduction Fibroblast Growth Factor Receptor Signaling Pathway	Cytokinesis Actin Filament Organization Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Neuron Remodeling Regulation Of Cell Migration Establishment Or Maintenance Of Actin Cytoskeleton Polarity Regulation Of Actin Cytoskeleton Organization Actin Filament Bundle Assembly
Pathways		FRS-mediated FGFR1 signaling FRS-mediated FGFR2 signaling FRS-mediated FGFR3 signaling FRS-mediated FGFR4 signaling RAF/MAP kinase cascade Activated NTRK2 signals through FRS2 and FRS3	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS		Menarche (age at onset) ( 25231870)	Bipolar disorder ( 21926972)
Interacting Genes		28 interacting genes: ADAMTSL4 BMPR2 CBY2 DDX5 FGFR1 GATA1 GRB14 GRB2 KARS1 MAPK1 MATK NOTCH2NLA NTRK1 NTRK2 NUMB PLSCR1 PRKCI PTPN11 RFX6 RND1 SH2B1 SOCS6 SPRY2 TCF4 TLE5 TNS1 TRIP6 VASP	12 interacting genes: ARHGAP5 CREB3L2 FRS2 FRS3 GRB7 ID3 PDE6D PLXNA1 PLXNB1 PLXNB2 UBXN11 ZNF212
Entrez ID		10817	27289
HPRD ID		06373	12357
Ensembl ID		ENSG00000137218	ENSG00000172602
Uniprot IDs		A0A140VJJ7 O43559	Q92730
PDB IDs		2KUP 2KUQ 2YS5 2YT2	2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?
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