NOXA1 and FAT1

Number of citations of the paper that reports this interaction (PubMedID 28129444)
3

Data Source:
BioGRID (two hybrid)

		NOXA1	FAT1
Description		NADPH oxidase activator 1	FAT atypical cadherin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol NADPH Oxidase Complex	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Apical Plasma Membrane Lamellipodium Filopodium Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Rac GTPase Binding	Calcium Ion Binding Protein Binding
	Biological Process	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Positive Regulation Of Catalytic Activity Regulation Of Respiratory Burst	Epithelial Cell Morphogenesis Actin Filament Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Establishment Or Maintenance Of Cell Polarity Cell-cell Signaling Anatomical Structure Morphogenesis Cell Migration Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Camera-type Eye Morphogenesis Cell-cell Adhesion
Pathways		RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS		Response to fenofibrate (total cholesterol levels) ( 27002377)	Alzheimer disease and age of onset ( 26830138) Carotid plaque burden ( 28282560) Chronotype ( 26955885) Heel bone mineral density ( 30598549) Macular thickness ( 30535121) Major depressive disorder ( 29317602) Medication use (calcium channel blockers) ( 31015401) Morning vs. evening chronotype ( 26955885) Obesity ( 21552555) PR interval ( 30046033) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		14 interacting genes: CACNA1A EP300 FAT1 MAPK1 MAPK11 NCF1 NOX1 NOXO1 PRKACA PRKCA PRKCG RAC1 RAC2 RIMBP3	12 interacting genes: CLK1 ENAH HOMER1 HOMER3 IGLL1 MT-ND1 NOXA1 SORBS2 TRAF4 TRIM14 UBC VASP
Entrez ID		10811	2195
HPRD ID		17644	02986
Ensembl ID		ENSG00000188747	ENSG00000083857
Uniprot IDs		Q86UR1	Q14517
PDB IDs
Enriched GO Terms of Interacting Partners?
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