FAT1 and IGLL1

Number of citations of the paper that reports this interaction (PubMedID 28129444)
3

Data Source:
BioGRID (two hybrid)

		FAT1	IGLL1
Description		FAT atypical cadherin 1	immunoglobulin lambda like polypeptide 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Apical Plasma Membrane Lamellipodium Filopodium Perinuclear Region Of Cytoplasm Extracellular Exosome	Extracellular Region External Side Of Plasma Membrane Membrane Immunoglobulin Complex, Circulating
	Molecular Function	Calcium Ion Binding Protein Binding	Antigen Binding Immunoglobulin Receptor Binding
	Biological Process	Epithelial Cell Morphogenesis Actin Filament Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Establishment Or Maintenance Of Cell Polarity Cell-cell Signaling Anatomical Structure Morphogenesis Cell Migration Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Camera-type Eye Morphogenesis Cell-cell Adhesion	Phagocytosis, Recognition Phagocytosis, Engulfment Immune Response Complement Activation, Classical Pathway Defense Response To Bacterium Innate Immune Response B Cell Receptor Signaling Pathway Positive Regulation Of B Cell Activation Leukocyte Migration
Pathways			Cell surface interactions at the vascular wall
Drugs			Copper
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		Alzheimer disease and age of onset ( 26830138) Carotid plaque burden ( 28282560) Chronotype ( 26955885) Heel bone mineral density ( 30598549) Macular thickness ( 30535121) Major depressive disorder ( 29317602) Medication use (calcium channel blockers) ( 31015401) Morning vs. evening chronotype ( 26955885) Obesity ( 21552555) PR interval ( 30046033) Urinary albumin-to-creatinine ratio ( 31630189)	Blood protein levels ( 30072576 29875488) Height ( 18391951) Migraine ( 21448238) Peripheral artery disease ( 25009551)
Interacting Genes		12 interacting genes: CLK1 ENAH HOMER1 HOMER3 IGLL1 MT-ND1 NOXA1 SORBS2 TRAF4 TRIM14 UBC VASP	2 interacting genes: FAT1 MYOC
Entrez ID		2195	3543
HPRD ID		02986	00905
Ensembl ID		ENSG00000083857	ENSG00000128322
Uniprot IDs		Q14517	P15814
PDB IDs			2H32 2H3N 2LKQ
Enriched GO Terms of Interacting Partners?
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