SPAG5 and LINGO1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SPAG5	LINGO1
Description		sperm associated antigen 5	leucine rich repeat and Ig domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Cytoplasm Midbody Centriolar Satellite Microtubule Plus-end Mitotic Spindle Mitotic Spindle Pole	Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix
	Molecular Function	Protein Binding Microtubule Binding	Epidermal Growth Factor Receptor Binding Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Spindle Organization Chromosome Segregation Positive Regulation Of Intracellular Transport Cell Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Protein Localization To Centrosome Regulation Of Metaphase Plate Congression Positive Regulation Of Spindle Assembly	Negative Regulation Of Axonogenesis
Pathways			Axonal growth inhibition (RHOA activation)
Drugs
Diseases
GWAS			Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Essential tremor ( 19182806) Feeling miserable ( 29500382) General factor of neuroticism ( 30867560) Hemoglobin A1c levels ( 29403010) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Neuroticism ( 27089181) Risky sexual behaviors (alcohol dependence interaction) ( 28990359)
Interacting Genes		44 interacting genes: AMOTL2 ARNT2 ATN1 BARD1 C1orf109 CCDC33 CCHCR1 CDC20B CDK1 CHCHD3 DCX EIF4E2 EIF4ENIF1 ENKD1 FBXO28 FMR1 GOLGA8EP GOLGA8F HAUS1 IQCE KANSL1 LGALS14 LINGO1 MID1 MID2 NLGN3 ODF1 ORC6 PIMREG POLR2L RBM41 SH2D4A SMARCE1 SNAP47 SNAPIN TSHZ3 TTC23 ZC2HC1C ZFC3H1 ZFYVE26 ZGPAT ZMAT2 ZNF385C ZNF688	8 interacting genes: EFEMP2 FBXW7 GOLGA2 KRTAP4-12 NGFR RTN4R SPAG5 TRIM27
Entrez ID		10615	84894
HPRD ID		10246	14322
Ensembl ID		ENSG00000076382	ENSG00000169783
Uniprot IDs		Q96R06	Q96FE5
PDB IDs			2ID5 4OQT
Enriched GO Terms of Interacting Partners?
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