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SPAG5 and POLR2L
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
381
Data Source:
BioGRID
(two hybrid)
SPAG5
POLR2L
Description
sperm associated antigen 5
RNA polymerase II subunit L
Image
No pdb structure
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Cytoplasm
Midbody
Centriolar Satellite
Microtubule Plus-end
Mitotic Spindle
Mitotic Spindle Pole
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
RNA Polymerase III Complex
RNA Polymerase I Complex
Cytosol
Molecular Function
Protein Binding
Microtubule Binding
DNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Zinc Ion Binding
Biological Process
Mitotic Sister Chromatid Segregation
Spindle Organization
Chromosome Segregation
Positive Regulation Of Intracellular Transport
Cell Division
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Protein Localization To Centrosome
Regulation Of Metaphase Plate Congression
Positive Regulation Of Spindle Assembly
MRNA Splicing, Via Spliceosome
Transcription-coupled Nucleotide-excision Repair
Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase I
Transcription By RNA Polymerase I
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Fibroblast Growth Factor Receptor Signaling Pathway
RNA Metabolic Process
Positive Regulation Of Type I Interferon Production
Somatic Stem Cell Population Maintenance
SnRNA Transcription By RNA Polymerase II
TRNA Transcription By RNA Polymerase III
Positive Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Viral Transcription
Regulation Of Gene Silencing By MiRNA
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
Cytosolic sensors of pathogen-associated DNA
MicroRNA (miRNA) biogenesis
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase III Chain Elongation
RNA Polymerase I Transcription Termination
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Drugs
Diseases
GWAS
Pulse pressure (
30578418
)
Interacting Genes
44 interacting genes:
AMOTL2
ARNT2
ATN1
BARD1
C1orf109
CCDC33
CCHCR1
CDC20B
CDK1
CHCHD3
DCX
EIF4E2
EIF4ENIF1
ENKD1
FBXO28
FMR1
GOLGA8EP
GOLGA8F
HAUS1
IQCE
KANSL1
LGALS14
LINGO1
MID1
MID2
NLGN3
ODF1
ORC6
PIMREG
POLR2L
RBM41
SH2D4A
SMARCE1
SNAP47
SNAPIN
TSHZ3
TTC23
ZC2HC1C
ZFC3H1
ZFYVE26
ZGPAT
ZMAT2
ZNF385C
ZNF688
23 interacting genes:
BANP
CCDC85B
CCN3
CHEK2
COIL
EXOSC5
L3MBTL3
NFKBIB
PHC2
POLR2A
POLR2B
POLR2C
POLR2D
POLR2E
POLR2G
POLR2H
REL
RPAP1
SNX7
SPAG5
THAP1
TP53BP2
ZBTB14
Entrez ID
10615
5441
HPRD ID
10246
01155
Ensembl ID
ENSG00000076382
ENSG00000177700
Uniprot IDs
Q96R06
P62875
PDB IDs
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6DRD
6O9L
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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