SPAG5 and CHCHD3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SPAG5	CHCHD3
Description		sperm associated antigen 5	coiled-coil-helix-coiled-coil-helix domain containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Cytoplasm Midbody Centriolar Satellite Microtubule Plus-end Mitotic Spindle Mitotic Spindle Pole	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane MICOS Complex Extracellular Exosome
	Molecular Function	Protein Binding Microtubule Binding	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Phosphatase Binding Molecular Adaptor Activity
	Biological Process	Mitotic Sister Chromatid Segregation Spindle Organization Chromosome Segregation Positive Regulation Of Intracellular Transport Cell Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Protein Localization To Centrosome Regulation Of Metaphase Plate Congression Positive Regulation Of Spindle Assembly	Negative Regulation Of Transcription By RNA Polymerase II Inner Mitochondrial Membrane Organization Mitochondrial Fusion Cristae Formation
Pathways			Mitochondrial protein import Cristae formation
Drugs
Diseases
GWAS			Chronotype ( 30696823) Food allergy ( 29030101) Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) ( 28820441) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Smoking status (ever vs never smokers) ( 30643258) Urinary potassium excretion ( 31409800)
Interacting Genes		44 interacting genes: AMOTL2 ARNT2 ATN1 BARD1 C1orf109 CCDC33 CCHCR1 CDC20B CDK1 CHCHD3 DCX EIF4E2 EIF4ENIF1 ENKD1 FBXO28 FMR1 GOLGA8EP GOLGA8F HAUS1 IQCE KANSL1 LGALS14 LINGO1 MID1 MID2 NLGN3 ODF1 ORC6 PIMREG POLR2L RBM41 SH2D4A SMARCE1 SNAP47 SNAPIN TSHZ3 TTC23 ZC2HC1C ZFC3H1 ZFYVE26 ZGPAT ZMAT2 ZNF385C ZNF688	24 interacting genes: AASS AMOTL2 BLZF1 CALCOCO2 CBY2 CCDC33 CCDC85B FANCL GMCL2 GOLGA2 KRT40 KRTAP4-12 LZTS2 NOTCH2NLA NUDT3 PDE4DIP RAB3IP RPGRIP1 SAMM50 SPAG5 SSX2IP TRAF1 TRIM27 USHBP1
Entrez ID		10615	54927
HPRD ID		10246	13044
Ensembl ID		ENSG00000076382	ENSG00000106554
Uniprot IDs		Q96R06	A4D1N4 B7Z1X9 C9JRZ6 Q9NX63
PDB IDs
Enriched GO Terms of Interacting Partners?
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