ERLIN1 and SEC22A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ERLIN1	SEC22A
Description		ER lipid raft associated 1	SEC22 homolog A, vesicle trafficking protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Protein-containing Complex	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Cholesterol Binding Ubiquitin Protein Ligase Binding	Transporter Activity Protein Binding
	Biological Process	Cholesterol Metabolic Process Ubiquitin-dependent ERAD Pathway SREBP Signaling Pathway Negative Regulation Of Cholesterol Biosynthetic Process Negative Regulation Of Fatty Acid Biosynthetic Process Transmembrane Transport	ER To Golgi Vesicle-mediated Transport Protein Transport
Pathways		ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis	COPII-mediated vesicle transport
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) General cognitive ability ( 29844566) HDL cholesterol ( 30275531) Heel bone mineral density ( 30598549) Liver enzyme levels ( 18940312) Response to radiotherapy in cancer (late toxicity) ( 24785509) Squamous cell lung carcinoma ( 28604730) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)	Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		4 interacting genes: AGR3 FA2H SEC22A TMEM199	11 interacting genes: DTX2 EDA ERLIN1 FATE1 LMNA MSR1 RNF5 SFTPC STX4 SYNE4 TMEM79
Entrez ID		10613	26984
HPRD ID		08502	15313
Ensembl ID		ENSG00000107566	ENSG00000121542
Uniprot IDs		O75477	Q96IW7
PDB IDs
Enriched GO Terms of Interacting Partners?
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