SAP18 and INCA1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SAP18	INCA1
Description		Sin3A associated protein 18	inhibitor of CDK, cyclin A1 interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm Cytosol Nuclear Body Nuclear Speck Exon-exon Junction Complex ASAP Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	Transcription Corepressor Activity RNA Binding Protein Binding	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Cyclin Binding Protein-containing Complex Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II MRNA Processing RNA Splicing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Nucleic Acid-templated Transcription	Negative Regulation Of Cell Proliferation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Apoptotic Signaling Pathway
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS			Intraocular pressure ( 29235454) Obesity-related traits ( 23251661)
Interacting Genes		12 interacting genes: HDAC1 IKZF1 INCA1 NOL12 POLE2 RBM39 RNPS1 RPS3A SIN3A SUFU TADA3 TSC22D2	39 interacting genes: ARMC7 CABP5 CCNA1 CDC23 CDK2 CDKN2D CHCHD2 COL8A1 CTNNBIP1 DAZAP2 DMRT3 DPH7 EPHB6 FHL2 FMR1 GRB2 HAUS1 NEK6 OSGIN1 PATE1 PTGER3 RAB5C RAMAC RBPMS RNF26 SAP18 SCNM1 SEC14L4 SPG21 SPOUT1 STAMBPL1 STK16 TRIM26 TRIP6 UBE2D4 UBXN2B VPS28 ZMYND19 ZNF205-AS1
Entrez ID		10284	388324
HPRD ID		04256	17150
Ensembl ID		ENSG00000150459	ENSG00000196388
Uniprot IDs		O00422	Q0VD86
PDB IDs		2HDE
Enriched GO Terms of Interacting Partners?
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