INCA1 and UBXN2B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		INCA1	UBXN2B
Description		inhibitor of CDK, cyclin A1 interacting protein 1	UBX domain protein 2B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Body	Cell Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol Spindle Pole Centrosome
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Cyclin Binding Protein-containing Complex Binding	Protein Binding Ubiquitin Binding
	Biological Process	Negative Regulation Of Cell Proliferation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Apoptotic Signaling Pathway	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Golgi Organization Nuclear Envelope Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome
Pathways
Drugs
Diseases
GWAS		Intraocular pressure ( 29235454) Obesity-related traits ( 23251661)	Gallstone disease ( 27094239) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Loneliness ( 27629369) Low density lipoprotein cholesterol levels ( 29403010) Medication use (HMG CoA reductase inhibitors) ( 31015401) Narcolepsy with cataplexy ( 23496005) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Total cholesterol levels ( 29403010) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		39 interacting genes: ARMC7 CABP5 CCNA1 CDC23 CDK2 CDKN2D CHCHD2 COL8A1 CTNNBIP1 DAZAP2 DMRT3 DPH7 EPHB6 FHL2 FMR1 GRB2 HAUS1 NEK6 OSGIN1 PATE1 PTGER3 RAB5C RAMAC RBPMS RNF26 SAP18 SCNM1 SEC14L4 SPG21 SPOUT1 STAMBPL1 STK16 TRIM26 TRIP6 UBE2D4 UBXN2B VPS28 ZMYND19 ZNF205-AS1	7 interacting genes: CRX INCA1 MEOX1 NGLY1 PPP1R11 VAT1L VCP
Entrez ID		388324	137886
HPRD ID		17150	18973
Ensembl ID		ENSG00000196388	ENSG00000215114
Uniprot IDs		Q0VD86	E5RJ36 Q14CS0
PDB IDs
Enriched GO Terms of Interacting Partners?
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