GPHN and ACADVL

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GPHN	ACADVL
Description		gephyrin	acyl-CoA dehydrogenase very long chain
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Postsynaptic Density Cell Junction Dendrite Postsynaptic Membrane Postsynaptic Specialization Postsynaptic Specialization Membrane	Nucleoplasm Nucleolus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol Mitochondrial Membrane Mitochondrial Nucleoid
	Molecular Function	Protein Binding ATP Binding Nitrate Reductase Activity Molybdopterin Cofactor Binding Metal Ion Binding Molybdopterin Adenylyltransferase Activity Molybdopterin Molybdotransferase Activity	Fatty-acyl-CoA Binding Long-chain-acyl-CoA Dehydrogenase Activity Very-long-chain-acyl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Mo-molybdopterin Cofactor Biosynthetic Process Establishment Of Synaptic Specificity At Neuromuscular Junction Response To Metal Ion Molybdenum Incorporation Into Molybdenum-molybdopterin Complex Molybdopterin Cofactor Biosynthetic Process Oxidation-reduction Process Glycine Receptor Clustering Gamma-aminobutyric Acid Receptor Clustering Postsynaptic Neurotransmitter Receptor Diffusion Trapping	Temperature Homeostasis Fatty Acid Beta-oxidation Response To Cold Energy Derivation By Oxidation Of Organic Compounds Epithelial Cell Differentiation Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase IRE1-mediated Unfolded Protein Response Negative Regulation Of Fatty Acid Biosynthetic Process Negative Regulation Of Fatty Acid Oxidation Regulation Of Cholesterol Metabolic Process
Pathways		Molybdenum cofactor biosynthesis	XBP1(S) activates chaperone genes Beta oxidation of palmitoyl-CoA to myristoyl-CoA
Drugs		Formic Acid Imidazole Propanoic Acid
Diseases		Hyperekplexia	Disorders of fatty-acid oxidation, including: Medium-chain (MC) acyl-CoA dehydrogenase (AD) deficiency (MCADD); Short-chain AD deficiency (SCADD) ; Short-branched-chain AD deficiency (SBCADD) ; Very long-chain AD deficiency (VLCADD) ; Long-chain 3-hydroxyacyl CoA dehydrogenase deficiency (LCHADD) ; Trifunctional protein deficiency (TFP); Carnitine palmitoyltransferase deficiency (CPT); Carnitine-acylcarnitine translocase deficiency (CACT); Systemic primary carnitine deficiency (CDSP)
GWAS		Depression (quantitative trait) ( 23290196) Pneumococcal meningitis ( 31092817) Tandem gait ( 26219847) Waist circumference adjusted for body mass index ( 28552196)	Metabolite levels ( 23823483)
Interacting Genes		13 interacting genes: ACADVL ARHGEF9 DYNLL1 DYNLL2 ENAH GABARAP GLRB KHDRBS1 MTOR PFN1 PIN1 SPATS1 TUBA4A	4 interacting genes: GPHN RPSA SIRT3 SOCS3
Entrez ID		10243	37
HPRD ID		04893	01940
Ensembl ID		ENSG00000171723	ENSG00000072778
Uniprot IDs		Q9NQX3	B3KPA6 P49748
PDB IDs		1JLJ	2UXW 3B96
Enriched GO Terms of Interacting Partners?
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