ABCC9 and LDHA

Number of citations of the paper that reports this interaction (PubMedID 12145195)
42

Data Source:
HPRD (in vivo)

		ABCC9	LDHA
Description		ATP binding cassette subfamily C member 9	lactate dehydrogenase A
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Inward Rectifying Potassium Channel Membrane Sarcomere Potassium Ion-transporting ATPase Complex	Nucleus Cytosol Membrane Extracellular Exosome
	Molecular Function	Cation Channel Activity Potassium Channel Activity ATP Binding Sulfonylurea Receptor Activity ATP-activated Inward Rectifier Potassium Channel Activity Potassium Channel Regulator Activity ATPase Activity Cation-transporting ATPase Activity Transmembrane Transporter Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Ion Channel Binding	L-lactate Dehydrogenase Activity Protein Binding Kinase Binding Identical Protein Binding Cadherin Binding NAD Binding
	Biological Process	Response To ATP Defense Response To Virus Transmembrane Transport Cardiac Conduction Potassium Ion Transmembrane Transport Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Regulation Of Cardiac Conduction Potassium Ion Import Across Plasma Membrane	Response To Hypoxia Lactate Metabolic Process Pyruvate Metabolic Process Glycolytic Process Response To Nutrient Response To Glucose NAD Metabolic Process Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Response To Estrogen Post-embryonic Animal Organ Development Response To CAMP Oxidation-reduction Process
Pathways		ATP sensitive Potassium channels ABC-family proteins mediated transport Ion homeostasis Defective ABCC9 causes dilated cardiomyopathy 10, familial atrial fibrillation 12 and hypertrichotic osteochondrodysplasia	Pyruvate metabolism
Drugs		ATP Glyburide Nicorandil	NADH Etheno-Nad Nicotinamide Oxamic Acid Stiripentol Copper Artenimol
Diseases		Atrial fibrillation
GWAS		Birth weight ( 27680694) Gout ( 22179738) Hippocampal sclerosis of aging ( 24770881) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Pulse pressure ( 30224653 30578418)	Amyloid A serum levels ( 21124955)
Interacting Genes		6 interacting genes: EEF1G HSPB2 KCNJ11 KCNJ8 LDHA STX1A	16 interacting genes: ABCC9 ACD DYNLL1 HNRNPD KCNJ11 LDHB MAPK10 NDRG1 PCNA POT1 PTPRF TERF1 TINF2 UPF2 XRN1 YWHAQ
Entrez ID		10060	3939
HPRD ID		03258	01025
Ensembl ID		ENSG00000069431	ENSG00000134333
Uniprot IDs		A0A024RAV7 O60706	P00338 V9HWB9
PDB IDs			1I10 4AJP 4JNK 4L4R 4L4S 4M49 4OJN 4OKN 4QO7 4QO8 4QSM 4QT0 4R68 4R69 4RLS 4ZVV 5IXS 5IXY 5W8H 5W8I 5W8J 5W8K 5W8L 5ZJD 5ZJE 5ZJF 6BAD 6BAG 6BAX 6BAZ 6BB0 6BB1 6BB2 6BB3 6MV8 6MVA
Enriched GO Terms of Interacting Partners?
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